Aaron Trinidade1, Joel A Goebel2. 1. Southend University Hospital NHS Foundation Trust, Prittlewell Chase, Westcliff-on-Sea, UK. 2. Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Abstract
OBJECTIVE: To present a systematic review of the current data on persistent postural-perceptual dizziness (PPPD), a useful and relatively new diagnosis for a disorder that has previously been known by many different names. In addition, to discuss diagnostic criteria and management strategies for this condition with the otologist in mind. DATA SOURCES: CINAHL, Embase, PubMed, Medline, PsycINFO, PubMed, Google Scholar. REVIEW METHOD: The phrase "persistent postural-perceptual dizziness" and its acronym "PPPD" were used. RESULTS: From 318 articles, 15 were selected for full analysis with respect to PPPD. Most were case-control studies, with one consensus paper from the Bárány Society available. Overall, the pathophysiology of PPPD remains relatively poorly understood, but is likely to be a maladaptive state to a variety of insults, including vestibular dysfunction and not a structural or psychiatric one. Cognitive behavioral therapy, vestibular rehabilitation, selective serotonin uptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs) all seem to have a role in its management. CONCLUSIONS: PPPD is useful as a diagnosis for those treating dizziness as it helps to define a conglomeration of symptoms that can seem otherwise vague and allows for more structured management plans in those suffering from it.
OBJECTIVE: To present a systematic review of the current data on persistent postural-perceptual dizziness (PPPD), a useful and relatively new diagnosis for a disorder that has previously been known by many different names. In addition, to discuss diagnostic criteria and management strategies for this condition with the otologist in mind. DATA SOURCES: CINAHL, Embase, PubMed, Medline, PsycINFO, PubMed, Google Scholar. REVIEW METHOD: The phrase "persistent postural-perceptual dizziness" and its acronym "PPPD" were used. RESULTS: From 318 articles, 15 were selected for full analysis with respect to PPPD. Most were case-control studies, with one consensus paper from the Bárány Society available. Overall, the pathophysiology of PPPD remains relatively poorly understood, but is likely to be a maladaptive state to a variety of insults, including vestibular dysfunction and not a structural or psychiatric one. Cognitive behavioral therapy, vestibular rehabilitation, selective serotonin uptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs) all seem to have a role in its management. CONCLUSIONS: PPPD is useful as a diagnosis for those treating dizziness as it helps to define a conglomeration of symptoms that can seem otherwise vague and allows for more structured management plans in those suffering from it.