Literature DB >> 30288596

Diagnosis and management of nocturia in current clinical practice: who are nocturia patients, and how do we treat them?

Siri Drangsholt1, Maria Juliana Arcila Ruiz2, Benoit Peyronnet3, Nirit Rosenblum2, Victor Nitti2, Benjamin Brucker2.   

Abstract

OBJECTIVE: To characterize the current evaluation, and efficacy of treatments in patients with the primary complaint of nocturia.
METHODS: A retrospective chart review was performed of new patient encounters seen in a tertiary urology practice from May 2010 to September 2016 with the primary diagnosis of nocturia (ICD-9 788.43 and ICD-10 R35.1).
RESULTS: 595 patients were identified. 403 met inclusion criteria. The median patient reported that nocturia episodes were 4 (1-20). 192 patients (48%) reported previous treatment for nocturia. After the index visit, a bladder diary (BD) was utilized in 50% of patients, with a 62% (n = 124) completion rate at follow-up visit. On BD analysis, the most common etiologies of nocturia were nocturnal polyuria 76% (n = 90) and overactive bladder in 21% (n = 26). Patient reported improvement with therapy after BD completion was 46% (n = 34), similar to patients without voiding diaries (43% improvement, n = 153). Anticholinergics and alpha blockers were the most commonly recommended drug, but no specific medication was associated with nocturia improvement. Oral desmopressin was used in 5% of patients.
CONCLUSION: Nocturia is a common condition and very commonly patients have sought treatment prior to presentation. Bladder diaries were recommended to half of the patients. Patient reported that improvement did not seem to correlate with completion of a bladder diary. Though most patients had NP the use of desmopressin was very low. Current treatments used in managing nocturia may lack efficacy.

Entities:  

Keywords:  Desmopressin; Frequency volume chart; Nocturia; Nocturnal polyuria

Mesh:

Substances:

Year:  2018        PMID: 30288596     DOI: 10.1007/s00345-018-2511-4

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  17 in total

1.  The standardisation of terminology in nocturia: report from the Standardisation Sub-committee of the International Continence Society.

Authors:  Philip van Kerrebroeck; Paul Abrams; David Chaikin; Jenny Donovan; David Fonda; Simon Jackson; Poul Jennum; Theodore Johnson; Gunnar Lose; Anders Mattiasson; Gary Robertson; Jeff Weiss
Journal:  Neurourol Urodyn       Date:  2002       Impact factor: 2.696

2.  Perception of nocturia and medical consulting behavior among community-dwelling women.

Authors:  Fong-Ying Chen; Yu-Tzu Dai; Chih-Kuang Liu; Hong-Jeng Yu; Cheng-Ying Liu; Tony Hsiu-Hsi Chen
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2006-07-28

3.  Desmopressin orally disintegrating tablet effectively reduces nocturia: results of a randomized, double-blind, placebo-controlled trial.

Authors:  Jeffrey P Weiss; Norman R Zinner; Bjarke M Klein; Jens Peter Nørgaard
Journal:  Neurourol Urodyn       Date:  2012-03-22       Impact factor: 2.696

Review 4.  The prevalence and causes of nocturia.

Authors:  J L H Ruud Bosch; Jeffrey P Weiss
Journal:  J Urol       Date:  2013-01       Impact factor: 7.450

5.  Changes in nocturia from medical treatment of benign prostatic hyperplasia: secondary analysis of the Department of Veterans Affairs Cooperative Study Trial.

Authors:  Theodore M Johnson; Karen Jones; William O Williford; Michael H Kutner; Muta M Issa; Herbert Lepor
Journal:  J Urol       Date:  2003-07       Impact factor: 7.450

Review 6.  A contemporary assessment of nocturia: definition, epidemiology, pathophysiology, and management--a systematic review and meta-analysis.

Authors:  Jean-Nicolas Cornu; Paul Abrams; Christopher R Chapple; Roger R Dmochowski; Gary E Lemack; Martin C Michel; Andrea Tubaro; Stephan Madersbacher
Journal:  Eur Urol       Date:  2012-07-20       Impact factor: 20.096

7.  Desmopressin in the treatment of nocturia: a double-blind, placebo-controlled study.

Authors:  Philip van Kerrebroeck; Masoumeh Rezapour; Ariane Cortesse; Joachim Thüroff; Anders Riis; Jens Peter Nørgaard
Journal:  Eur Urol       Date:  2007-01-16       Impact factor: 20.096

8.  Lower urinary tract symptoms: lack of change in prevalence and help-seeking behaviour in two population-based surveys of women in 1991 and 2007.

Authors:  Anna-Lena Wennberg; Ulla Molander; Magnus Fall; Christer Edlund; Ralph Peeker; Ian Milsom
Journal:  BJU Int       Date:  2009-04-21       Impact factor: 5.588

9.  Multicenter phase III trial studying trospium chloride in patients with overactive bladder.

Authors:  Delbert Rudy; Kevin Cline; Richard Harris; Kenneth Goldberg; Roger Dmochowski
Journal:  Urology       Date:  2006-02       Impact factor: 2.649

10.  Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland.

Authors:  Kari A O Tikkinen; Theodore M Johnson; Teuvo L J Tammela; Harri Sintonen; Jari Haukka; Heini Huhtala; Anssi Auvinen
Journal:  Eur Urol       Date:  2009-04-03       Impact factor: 20.096

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  3 in total

1.  Nocturia in Patients With Multiple Sclerosis.

Authors:  Benoit Peyronnet; Lauren B Krupp; W Stuart Reynolds; Xavier Gamé; Gérard Amarenco; Jean-Nicolas Cornu; Lana Zhovtis Ryerson; Carrie Lyn Sammarco; Jonathan E Howard; Robert W Charlson; Roger R Dmochowski; Benjamin M Brucker
Journal:  Rev Urol       Date:  2019

2.  Obstructive sleep apnea syndrome should always be screened in patients complaining of nocturia.

Authors:  Vincent Misraï; Helene Charbonneau; David Attias; Atul Pathak
Journal:  World J Urol       Date:  2018-10-22       Impact factor: 4.226

3.  The clinical features and predictive factors of nocturnal enuresis in adult men.

Authors:  Qi-Xiang Song; Lei Wang; Xin Cheng; Yiru Hao; Zhiyong Liu; Paul Abrams
Journal:  BJU Int       Date:  2020-07-24       Impact factor: 5.588

  3 in total

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