Literature DB >> 30288397

The Great Recession and Immune Function.

Elizabeth McClure1, Lydia Feinstein2, Sara Ferrando-Martínez3, Manuel Leal4, Sandro Galea5, Allison E Aiello1.   

Abstract

The Great Recession precipitated unprecedented home foreclosures increases, but documentation of related neighborhood changes and population health is scant. Using the Detroit Neighborhood Health Study (N = 277), we examined associations between neighborhood-level recession indicators and thymic function, a life course immunological health indicator. In covariate-adjusted multilevel models, each 10 percentage point increase in abandoned home prevalence and 1 percentage point increase in 2009 home foreclosures was associated with 1.7-year and 3.3-year increases in thymic aging, respectively. Associations attenuated after adjustment for neighborhood-level social cohesion, suggesting community ties may buffer recession-related immune aging. Effects of neighborhood stressors were strongest in middle-income households, supporting theory of excess vulnerability in this group. Future research should assess whether ongoing foreclosure and blight reduction efforts improve health for residents of recession impacted neighborhoods.

Entities:  

Keywords:  Detroit; immunity; immunosenescence; neighborhood; social determinants of health; thymic function

Year:  2018        PMID: 30288397      PMCID: PMC6168205     

Source DB:  PubMed          Journal:  RSF


  47 in total

Review 1.  The (mis)estimation of neighborhood effects: causal inference for a practicable social epidemiology.

Authors:  J Michael Oakes
Journal:  Soc Sci Med       Date:  2004-05       Impact factor: 4.634

2.  Modeling neighborhood effects: the futility of comparing mixed and marginal approaches.

Authors:  S V Subramanian; A James O'Malley
Journal:  Epidemiology       Date:  2010-07       Impact factor: 4.822

3.  Examination of how neighborhood definition influences measurements of youths' access to tobacco retailers: a methodological note on spatial misclassification.

Authors:  Dustin T Duncan; Ichiro Kawachi; S V Subramanian; Jared Aldstadt; Steven J Melly; David R Williams
Journal:  Am J Epidemiol       Date:  2013-10-22       Impact factor: 4.897

4.  A reliable and simplified sj/beta-TREC ratio quantification method for human thymic output measurement.

Authors:  Sara Ferrando-Martínez; Jaime M Franco; Ezequiel Ruiz-Mateos; Ana Hernández; Antonio Ordoñez; Encarnación Gutierrez; Manuel Leal
Journal:  J Immunol Methods       Date:  2009-11-15       Impact factor: 2.303

5.  Filling the gaps: spatial interpolation of residential survey data in the estimation of neighborhood characteristics.

Authors:  Amy H Auchincloss; Ana V Diez Roux; Daniel G Brown; Trivellore E Raghunathan; Christine A Erdmann
Journal:  Epidemiology       Date:  2007-07       Impact factor: 4.822

6.  Housing instability and health: findings from the Michigan Recession and Recovery Study.

Authors:  Sarah A Burgard; Kristin S Seefeldt; Sarah Zelner
Journal:  Soc Sci Med       Date:  2012-09-01       Impact factor: 4.634

Review 7.  Effects of stress on immune function: the good, the bad, and the beautiful.

Authors:  Firdaus S Dhabhar
Journal:  Immunol Res       Date:  2014-05       Impact factor: 2.829

8.  Home foreclosure and risk of psychiatric morbidity during the recent financial crisis.

Authors:  K A McLaughlin; A Nandi; K M Keyes; M Uddin; A E Aiello; S Galea; K C Koenen
Journal:  Psychol Med       Date:  2011-11-21       Impact factor: 7.723

9.  Changes in thymic function with age and during the treatment of HIV infection.

Authors:  D C Douek; R D McFarland; P H Keiser; E A Gage; J M Massey; B F Haynes; M A Polis; A T Haase; M B Feinberg; J L Sullivan; B D Jamieson; J A Zack; L J Picker; R A Koup
Journal:  Nature       Date:  1998-12-17       Impact factor: 49.962

Review 10.  The impact of economic crises on social inequalities in health: what do we know so far?

Authors:  Amaia Bacigalupe; Antonio Escolar-Pujolar
Journal:  Int J Equity Health       Date:  2014-07-25
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Authors:  Lilly Shanahan; Sherika N Hill; Lauren M Gaydosh; Annekatrin Steinhoff; E Jane Costello; Kenneth A Dodge; Kathleen Mullan Harris; William E Copeland
Journal:  Am J Public Health       Date:  2019-04-18       Impact factor: 9.308

2.  Sociodemographic Differences in Population-Level Immunosenescence in Older Age.

Authors:  Grace A Noppert; Rebecca C Stebbins; Jennifer Beam Dowd; Allison E Aiello
Journal:  medRxiv       Date:  2022-03-07

3.  Blood levels of T-Cell Receptor Excision Circles (TRECs) provide an index of exposure to traumatic stress in mice and humans.

Authors:  Kenneth M McCullough; Seyma Katrinli; Jakob Hartmann; Adriana Lori; Claudia Klengel; Galen Missig; Torsten Klengel; Nicole A Langford; Emily L Newman; Kasey J Anderson; Alicia K Smith; F Ivy Carroll; Kerry J Ressler; William A Carlezon
Journal:  Transl Psychiatry       Date:  2022-10-03       Impact factor: 7.989

  3 in total

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