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Literature DB >> 3028817

Activity of esterases in plasma from Ghanaian and British subjects.

F M Williams, E N Nicholson, N W Woolhouse, K K Adjepon-Yamoah, M D Rawlins.

Abstract

We have measured aspirin esterase, cholinesterase, paraoxonase, and phenylacetate esterase activities in samples of plasma from British and Ghanaian subjects. Aspirin esterase, paraoxonase, and phenylacetate esterase activities were significantly lower in Ghanaians compared with British subjects. However, cholinesterase activities were similar in Ghanaian and British plasma samples. The lower esterase activities in Ghanaian plasma samples may result in higher circulating concentrations and greater pharmacological effects of drugs such as aspirin.

Entities: Chemical Gene

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Year: 1986 PMID： 3028817 DOI： 10.1007/BF00613529

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

12 in total

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6 in total

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Authors: F M Williams; S I Asad; M H Lessof; M D Rawlins
Journal: Eur J Clin Pharmacol Date: 1987 Impact factor: 2.953

2. Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases.

Authors: Sandi L Navarro; Misty R Saracino; Karen W Makar; Sushma S Thomas; Lin Li; Yingye Zheng; Lisa Levy; Yvonne Schwarz; Jeannette Bigler; John D Potter; Johanna W Lampe
Journal: J Nutrigenet Nutrigenomics Date: 2011-05-28

6. Serum aspirin esterase is strongly associated with glucose and lipids in healthy subjects: different association patterns in subjects with type 2 diabetes mellitus.

Authors: Kazuhiko Kotani; Satoshi Kimura; Tetsu Ebara; Russell Caccavello; Alejandro Gugliucci
Journal: Diabetol Metab Syndr Date: 2010-07-27 Impact factor: 3.320