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Literature DB >> 3028808

Multi-system coxsackievirus B-6 infection with findings suggestive of diabetes mellitus.

G Nigro, M E Pacella, E Patanè, M Midulla.

Abstract

A fatal case of Coxsackievirus B-6 (CBV-6) infection in a 4 1/2-year-old girl is reported. The disease was initially characterized by a severe meningoencephalitis and, successively, by the appearance of hyperglycaemia and glycosuria, concomitantly with complement-fixing-islet cell antibodies (CF-ICA) and ICA, diarrhoea, electrolyte disorders, arrhythmia and decrease of the IgG levels, suggesting a multi-system involvement. CBV-6 was identified by isolation from stool and cerebrospinal fluid and by detection of specific IgM antibodies.

Entities: Disease Species

Mesh：

Year: 1986 PMID： 3028808 DOI： 10.1007/BF02429065

Source DB: PubMed Journal: Eur J Pediatr ISSN： 0340-6199 Impact factor: 3.183

20 in total

1. Virus-tissue union and the pathogenesis of enterovirus infections.

Authors: C M KUNIN
Journal: J Immunol Date: 1962-05 Impact factor: 5.422

2. Hemagglutinin variants of reovirus type 3 have altered central nervous system tropism.

Authors: D R Spriggs; R T Bronson; B N Fields
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3. Enterovirus infections in the neonate.

Authors: S Krajden; P J Middleton
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4. The mononuclear phagocyte system: role in expression of immunocompetence in neonatal and adult life.

Authors: R M Blaese; D G Poplack; A V Muchmore
Journal: Pediatrics Date: 1979-11 Impact factor: 7.124

5. Specificity of IgM antibodies in acute human coxsackievirus B infections, analysed by indirect solid phase enzyme immunoassay and immunoblot technique.

Authors: R Dörries; V ter Meulen
Journal: J Gen Virol Date: 1983-01 Impact factor: 3.891

6. Complement-fixing islet-cell antibodies in type-I diabetes: possible monitors of active beta-cell damage.

Authors: G F Bottazzo; B M Dean; A N Gorsuch; A G Cudworth; D Doniach
Journal: Lancet Date: 1980-03-29 Impact factor: 79.321

7. Virologic, immunologic, and genetic factors in insulin-dependent diabetes mellitus.

Authors: H F Champsaur; G F Bottazzo; J Bertrams; R Assan; C Bach
Journal: J Pediatr Date: 1982-01 Impact factor: 4.406

8. Virus-induced diabetes mellitus. Glucose abnormalities produced in mice by the six members of the Coxsackie B virus group.

Authors: A Toniolo; T Onodera; G Jordan; J W Yoon; A L Notkins
Journal: Diabetes Date: 1982-06 Impact factor: 9.461

Multi-system coxsackievirus B-6 infection with findings suggestive of diabetes mellitus.

1. Virus-tissue union and the pathogenesis of enterovirus infections.

2. Hemagglutinin variants of reovirus type 3 have altered central nervous system tropism.

3. Enterovirus infections in the neonate.

4. The mononuclear phagocyte system: role in expression of immunocompetence in neonatal and adult life.

5. Specificity of IgM antibodies in acute human coxsackievirus B infections, analysed by indirect solid phase enzyme immunoassay and immunoblot technique.

6. Complement-fixing islet-cell antibodies in type-I diabetes: possible monitors of active beta-cell damage.

7. Virologic, immunologic, and genetic factors in insulin-dependent diabetes mellitus.

8. Virus-induced diabetes mellitus. Glucose abnormalities produced in mice by the six members of the Coxsackie B virus group.

9. The location and nature of enterovirus receptors in susceptible cells.

10. Virus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus.

1. Coxsackie B4 viruses with the potential to damage beta cells of the islets are present in clinical isolates.

2. Group B coxsackievirus diabetogenic phenotype correlates with replication efficiency.

3. Mononucleosis-like syndrome associated with a multisystem Coxsackie virus type B3 infection in adolescence.

Review 4. Diabetes mellitus due to viruses--some recent developments.