Literature DB >> 30288000

Lymphatic Microsurgical Preventing Healing Approach (LYMPHA) for Prevention of Breast Cancer-Related Lymphedema-a Preliminary Report.

Juhi Agrawal1, Sandeep Mehta1, Ashish Goel1, Pankaj Kumar Pande1, Kapil Kumar1.   

Abstract

Lymphatic microsurgical preventing healing approach (LYMPHA) for prevention of breast cancer-related lymphedema (BCRL)-a preliminary report BCRL-is a chronic debilitating condition which impairs quality of life of breast cancer survivors. The aim is to study the feasibility of preventing lymphedema by performing "Lymphatic Microsurgical Preventive Healing Approach (LYMPHA)." Patients undergoing breast cancer surgery with complete nodal dissection were taken up for the study. After the standard axillary nodal dissection, lymphatics were identified by the help of blue dye and were anastomosed with a tributary to the axillary vein. Post-operatively, patients were followed up clinically for development of lymphedema and lymphoscintigraphy was performed after treatment completion. A total of 35 patients were enrolled for the study. The average BMI was 29.5. LYMPHA was feasible in all cases. The number of lymphatics identified was 1 to 5 per axilla. Two patients developed transient lymphedema which resolved with conservative therapy and patients were able to discontinue the compression garment. Follow-up lymphoscintigraphy is performed in two patients, which showed normal lymphatic flow. LYMPHA is a feasible technique, not difficult to perform, takes a short time, is accomplished in same general anesthesia as for axillary dissection, and gives no extra scar. The early results are promising and long-term follow-up may make the procedure as a routine.

Entities:  

Keywords:  Axillary lymph node dissection; Breast cancer; Lymphovenous anastomosis; Microsurgery; Secondary lymphedema

Year:  2018        PMID: 30288000      PMCID: PMC6154369          DOI: 10.1007/s13193-018-0731-0

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  16 in total

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Authors:  J A Petrek; R T Senie; M Peters; P P Rosen
Journal:  Cancer       Date:  2001-09-15       Impact factor: 6.860

Review 2.  Cancer treatment and survivorship statistics, 2012.

Authors:  Rebecca Siegel; Carol DeSantis; Katherine Virgo; Kevin Stein; Angela Mariotto; Tenbroeck Smith; Dexter Cooper; Ted Gansler; Catherine Lerro; Stacey Fedewa; Chunchieh Lin; Corinne Leach; Rachel Spillers Cannady; Hyunsoon Cho; Steve Scoppa; Mark Hachey; Rebecca Kirch; Ahmedin Jemal; Elizabeth Ward
Journal:  CA Cancer J Clin       Date:  2012-06-14       Impact factor: 508.702

3.  Surgical prevention of arm lymphedema after breast cancer treatment.

Authors:  Francesco M Boccardo; Federico Casabona; Daniele Friedman; Maria Puglisi; Franco De Cian; Filippo Ansaldi; Corradino Campisi
Journal:  Ann Surg Oncol       Date:  2011-03-03       Impact factor: 5.344

Review 4.  Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis.

Authors:  Tracey DiSipio; Sheree Rye; Beth Newman; Sandi Hayes
Journal:  Lancet Oncol       Date:  2013-03-27       Impact factor: 41.316

5.  Lymphatic microsurgical preventing healing approach (LYMPHA) for primary surgical prevention of breast cancer-related lymphedema: over 4 years follow-up.

Authors:  Francesco Boccardo; Federico Casabona; Franco De Cian; Franco DeCian; Daniele Friedman; Federica Murelli; Maria Puglisi; Corrado C Campisi; Lidia Molinari; Stefano Spinaci; Sara Dessalvi; Corradino Campisi
Journal:  Microsurgery       Date:  2014-03-26       Impact factor: 2.425

6.  Post-breast cancer lymphedema: incidence increases from 12 to 30 to 60 months.

Authors:  J M Armer; B R Stewart
Journal:  Lymphology       Date:  2010-09       Impact factor: 1.286

7.  A Single-Site Technique of Multiple Lymphatic-Venous Anastomoses for the Treatment of Peripheral Lymphedema: Long-Term Clinical Outcome.

Authors:  Corrado Cesare Campisi; Melissa Ryan; Francesco Boccardo; Corradino Campisi
Journal:  J Reconstr Microsurg       Date:  2015-06-01       Impact factor: 2.873

8.  The effect of prophylactic lymphovenous anastomosis and shunts for preventing cancer-related lymphedema: a systematic review and meta-analysis.

Authors:  Mads G Jørgensen; Navid M Toyserkani; Jens A Sørensen
Journal:  Microsurgery       Date:  2017-03-28       Impact factor: 2.425

9.  Single Institution Experience with Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) for the Primary Prevention of Lymphedema.

Authors:  Sheldon Feldman; Hannah Bansil; Jeffrey Ascherman; Robert Grant; Billie Borden; Peter Henderson; Adewuni Ojo; Bret Taback; Margaret Chen; Preya Ananthakrishnan; Amiya Vaz; Fatih Balci; Chaitanya R Divgi; David Leung; Christine Rohde
Journal:  Ann Surg Oncol       Date:  2015-07-23       Impact factor: 5.344

10.  The psychological morbidity of breast cancer-related arm swelling. Psychological morbidity of lymphoedema.

Authors:  M B Tobin; H J Lacey; L Meyer; P S Mortimer
Journal:  Cancer       Date:  1993-12-01       Impact factor: 6.860

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  2 in total

1.  Primary Prevention of Cancer-Related Lymphedema Using Preventive Lymphatic Surgery: Systematic Review and Meta-analysis.

Authors:  Pedro Ciudad; Joseph M Escandón; Valeria P Bustos; Oscar J Manrique; Juste Kaciulyte
Journal:  Indian J Plast Surg       Date:  2022-02-25

2.  Immediate Lymphatic Reconstruction during Axillary Node Dissection for Breast Cancer: A Systematic Review and Meta-analysis.

Authors:  W K Fraser Hill; Melina Deban; Alexander Platt; Priscilla Rojas-Garcia; Evan Jost; Claire Temple-Oberle
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-05-09
  2 in total

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