Literature DB >> 30287999

Reconstruction in Breast Conservation Therapy-Single Tertiary Care Institution Experience with 472 Patients.

Juhi Agrawal1, Sandeep Mehta1, Ashish Goel2, Veda Padmapriya Selvakumar3, Kapil Kumar2, Pankaj Kumar Pande2.   

Abstract

Breast conservation therapy (BCT) is now internationally accepted treatment for early breast cancer. Despite of high incidence of carcinoma breast in India, BCT rates are very low as compared to the west. In this article, we wish to share our experience of breast conservation with oncoplasty in Indian women. A retrospective analysis of case records of patients treated with oncoplastic breast conservation from January 2009 to June 2014 in a single surgical oncology unit in a tertiary cancer institute. Demographic patient data, stage of disease, location of primary tumour, use of neo-adjuvant chemotherapy if received, tumour size and breast size ratio, reconstruction method used, post-operative complications and aesthetic score of patients were analysed. Various methods of oncoplasty and partial breast reconstruction used are discussed. Four hundred and seventy-two patient records were found suitable for analysis. Most common stage of presentation was T2N0 in 189 patients (40%). Forty-one patients received neo-adjuvant chemotherapy (NACT). Tumour arising in upper outer quadrant was most common site, seen in 268 (56.7%). The most common method of reconstruction was volume displacement, done in 57.6% patients. Overall surgical complications included wound infection with or without dehiscence, seroma formation, partial flap necrosis and fat necrosis. Cosmesis was found to be excellent in 23.09% and good in 58.47% at 6-month follow-up. Breast conservation with oncoplasty is oncologically safe for early breast cancer treatment and has good cosmetic outcome with high patient satisfaction rates. Its practice should be encouraged in Indian set-up also.

Entities:  

Keywords:  Early breast cancer; Fasciocutaneous flap; Latissimus dorsi flap; Oncoplasty; Volume displacement; Volume replacement

Year:  2017        PMID: 30287999      PMCID: PMC6154353          DOI: 10.1007/s13193-017-0663-0

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  28 in total

Review 1.  Breast-sparing reconstruction with latissimus dorsi miniflaps.

Authors:  R M Rainsbury
Journal:  Eur J Surg Oncol       Date:  2002-12       Impact factor: 4.424

2.  Breast-conserving therapy for centrally located breast cancer.

Authors:  Florian Fitzal; Martina Mittlboeck; Herwig Trischler; Wilfried Krois; Greta Nehrer; Maria Deutinger; Raimund Jakesz; Michael Gnant
Journal:  Ann Surg       Date:  2008-03       Impact factor: 12.969

3.  Evaluation of surgical outcomes following oncoplastic breast surgery in early breast cancer and comparison with conventional breast conservation surgery.

Authors:  Ashutosh Chauhan; Mala Mathur Sharma
Journal:  Med J Armed Forces India       Date:  2015-12-13

4.  Breast conservation in locally advanced breast cancer.

Authors:  V Parmar; R A Badwe
Journal:  Indian J Surg Oncol       Date:  2010-08-07

Review 5.  Optimizing conservative breast surgery.

Authors:  Julie A Margenthaler
Journal:  J Surg Oncol       Date:  2011-03-15       Impact factor: 3.454

6.  Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer.

Authors:  J A Jacobson; D N Danforth; K H Cowan; T d'Angelo; S M Steinberg; L Pierce; M E Lippman; A S Lichter; E Glatstein; P Okunieff
Journal:  N Engl J Med       Date:  1995-04-06       Impact factor: 91.245

7.  10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study.

Authors:  Marissa C van Maaren; Linda de Munck; Geertruida H de Bock; Jan J Jobsen; Thijs van Dalen; Sabine C Linn; Philip Poortmans; Luc J A Strobbe; Sabine Siesling
Journal:  Lancet Oncol       Date:  2016-06-22       Impact factor: 41.316

8.  Aesthetic outcomes in breast conservation therapy.

Authors:  Howard T Wang; Constance M Barone; Megan B Steigelman; Morton Kahlenberg; Dennis Rousseau; Jamie Berger; Allison Daum; Delio P Ortegon
Journal:  Aesthet Surg J       Date:  2008 Mar-Apr       Impact factor: 4.283

9.  Surgical patterns of care in patients with invasive breast cancer treated with neoadjuvant systemic therapy and breast magnetic resonance imaging: results of a secondary analysis of TBCRC 017.

Authors:  Kandace P McGuire; E Shelley Hwang; Alan Cantor; Mehra Golshan; Funda Meric-Bernstam; Janet K Horton; Rita Nanda; Keith D Amos; Andres Forero; Cliff A Hudis; Ingrid Meszoely; Jennifer F De Los Santos
Journal:  Ann Surg Oncol       Date:  2014-07-25       Impact factor: 5.344

10.  Assessment of cosmetic outcome of oncoplastic breast conservation surgery in women with early breast cancer: a prospective cohort study.

Authors:  G Adimulam; V R Challa; A Dhar; S Chumber; V Seenu; A Srivastava
Journal:  Indian J Cancer       Date:  2014 Jan-Mar       Impact factor: 1.224

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  1 in total

1.  Outcome reporting in therapeutic mammaplasty: a systematic review.

Authors:  Alice Lee; Richard M Kwasnicki; Hasaan Khan; Yasmin Grant; Abigail Chan; Angela E E Fanshawe; Daniel R Leff
Journal:  BJS Open       Date:  2021-11-09
  1 in total

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