Literature DB >> 30287647

Smoothening out the patches.

Anselm Sommer1,2, Mark A Lemmon3,2.   

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Year:  2018        PMID： 30287647      PMCID： PMC6421564          DOI： 10.1126/science.aav1025

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  13 in total

1.  Structural Basis of Smoothened Activation in Hedgehog Signaling.

Authors:  Pengxiang Huang; Sanduo Zheng; Bradley M Wierbowski; Youngchang Kim; Daniel Nedelcu; Laura Aravena; Jing Liu; Andrew C Kruse; Adrian Salic
Journal:  Cell       Date:  2018-05-24       Impact factor: 41.582

2.  Structure of human Niemann-Pick C1 protein.

Authors:  Xiaochun Li; Jiawei Wang; Elias Coutavas; Hang Shi; Qi Hao; Günter Blobel
Journal:  Proc Natl Acad Sci U S A       Date:  2016-06-15       Impact factor: 11.205

Review 3.  Hedgehog Signaling: From Basic Biology to Cancer Therapy.

Authors:  Fujia Wu; Yu Zhang; Bo Sun; Andrew P McMahon; Yu Wang
Journal:  Cell Chem Biol       Date:  2017-03-09       Impact factor: 8.116

4.  Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium.

Authors:  Benjamin R Myers; Lila Neahring; Yunxiao Zhang; Kelsey J Roberts; Philip A Beachy
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-11       Impact factor: 11.205

Review 5.  Smoothened goes molecular: new pieces in the hedgehog signaling puzzle.

Authors:  Jacqueline M McCabe; Daniel J Leahy
Journal:  J Biol Chem       Date:  2014-12-17       Impact factor: 5.157

6.  Structures of human Patched and its complex with native palmitoylated sonic hedgehog.

Authors:  Xiaofeng Qi; Philip Schmiege; Elias Coutavas; Jiawei Wang; Xiaochun Li
Journal:  Nature       Date:  2018-07-11       Impact factor: 49.962

7.  Patched acts catalytically to suppress the activity of Smoothened.

Authors:  J Taipale; M K Cooper; T Maiti; P A Beachy
Journal:  Nature       Date:  2002-08-22       Impact factor: 49.962

8.  Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B.

Authors:  Peng Chen; Liang Tao; Tianyu Wang; Jie Zhang; Aina He; Kwok-Ho Lam; Zheng Liu; Xi He; Kay Perry; Min Dong; Rongsheng Jin
Journal:  Science       Date:  2018-05-11       Impact factor: 47.728

9.  The hedgehog receptor patched is involved in cholesterol transport.

Authors:  Michel Bidet; Olivier Joubert; Benoit Lacombe; Marine Ciantar; Rony Nehmé; Patrick Mollat; Lionel Brétillon; Hélène Faure; Robert Bittman; Martial Ruat; Isabelle Mus-Veteau
Journal:  PLoS One       Date:  2011-09-08       Impact factor: 3.240

10.  Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.

Authors:  Xianjun Zhang; Fei Zhao; Yiran Wu; Jun Yang; Gye Won Han; Suwen Zhao; Andrii Ishchenko; Lintao Ye; Xi Lin; Kang Ding; Venkatasubramanian Dharmarajan; Patrick R Griffin; Cornelius Gati; Garrett Nelson; Mark S Hunter; Michael A Hanson; Vadim Cherezov; Raymond C Stevens; Wenfu Tan; Houchao Tao; Fei Xu
Journal:  Nat Commun       Date:  2017-05-17       Impact factor: 14.919
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  2 in total

Review 1.  Teaching an old dog new tricks: reactivated developmental signaling pathways regulate ABCB1 and chemoresistance in cancer.

Authors:  Wing-Kee Lee; Thévenod Frank
Journal:  Cancer Drug Resist       Date:  2021-06-19

2.  Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened.

Authors:  George Hedger; Heidi Koldsø; Matthieu Chavent; Christian Siebold; Rajat Rohatgi; Mark S P Sansom
Journal:  Structure       Date:  2018-12-27       Impact factor: 5.006
  2 in total

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