Sheetal Kapse1, Sanidhya Surana2, M Satish3, Syed Erfan Hussain4, Sunil Vyas4, Deepak Thakur5. 1. Fellow, Maxillofacial Trauma, Association of Oral and Maxillofacial Surgeons of India, Bangalore, India); Private practitioner, Raipur, Chhattisgarh, India. Electronic address: sheetal.kapse@yahoo.com. 2. Private practitioner at Swasthya Sanchay Dental Clinic, Balod, Durg, Chhattisgarh, India. 3. Professor and Head of Department, Department of Oral and Maxillofacial Surgery at Anil Neerukonda Institute of Dental Sciences, Visakhapatnam, Andhra Pradesh, India. 4. Private practitioner, Raipur, Chhattisgarh, India. 5. Professor, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
Abstract
OBJECTIVE: The aim of this study was to evaluate the efficacy of platelet-rich fibrin (PRF) in the healing of impacted mandibular third molar (M3) extraction sockets. STUDY DESIGN: This study included 30 patients with bilaterally symmetric impacted M3 (N = 60) requiring transalveolar extraction. All patients were assigned numbers randomly; left-sided M3 patients with odd numbers and right-sided patients with even numbers were categorized into group A (test group), and the other side of the mouth was classified as "group B" (control group). Group A M3 extraction sockets received PRF, whereas group B sockets were closed without PRF. Patients were evaluated for pain and swelling on postoperative days 1, 3, 7, and 14. Bone healing was compared on postoperative weeks 8 and 16. Analysis of variance (ANOVA) and Tukey's multiple comparison tests were applied for statistical analysis. RESULTS: A total of 30 patients, ages 18 to 40 years, participated in this study. The overall postoperative pain score (visual analogue scale [VAS]) and facial swelling percentages were lower for group A compared with group B (P < .05). Early bone healing was also evident on postoperative radiographs obtained at weeks 8 and 16 in group A (P < .001). CONCLUSIONS: The use of autologous PRF aids in earlier and better wound healing in a controlled manner.
RCT Entities:
OBJECTIVE: The aim of this study was to evaluate the efficacy of platelet-rich fibrin (PRF) in the healing of impacted mandibular third molar (M3) extraction sockets. STUDY DESIGN: This study included 30 patients with bilaterally symmetric impacted M3 (N = 60) requiring transalveolar extraction. All patients were assigned numbers randomly; left-sided M3 patients with odd numbers and right-sided patients with even numbers were categorized into group A (test group), and the other side of the mouth was classified as "group B" (control group). Group A M3 extraction sockets received PRF, whereas group B sockets were closed without PRF. Patients were evaluated for pain and swelling on postoperative days 1, 3, 7, and 14. Bone healing was compared on postoperative weeks 8 and 16. Analysis of variance (ANOVA) and Tukey's multiple comparison tests were applied for statistical analysis. RESULTS: A total of 30 patients, ages 18 to 40 years, participated in this study. The overall postoperative pain score (visual analogue scale [VAS]) and facial swelling percentages were lower for group A compared with group B (P < .05). Early bone healing was also evident on postoperative radiographs obtained at weeks 8 and 16 in group A (P < .001). CONCLUSIONS: The use of autologous PRF aids in earlier and better wound healing in a controlled manner.
Authors: Edmund Bailey; Wafa Kashbour; Neha Shah; Helen V Worthington; Tara F Renton; Paul Coulthard Journal: Cochrane Database Syst Rev Date: 2020-07-26
Authors: Anna Starzyńska; Magdalena Kaczoruk-Wieremczuk; Michele Antonio Lopez; Pier Carmine Passarelli; Paulina Adamska Journal: Int J Environ Res Public Health Date: 2021-12-18 Impact factor: 3.390