| Literature DB >> 30286335 |
Michael P Mannino1, Jagodige P Yasomanee1, Alexei V Demchenko2.
Abstract
In an attempt to refine the H-bond-mediated Aglycone Delivery (HAD) glycosylation reaction reported herein is the synthesis of β-glucosides using an ethylthio glucoside donor equipped with the remote 6-O-picoloyl substituent. Upon examining various aliphatic, aromatic, and carbohydrate acceptors, it was determined that both electronic and steric factors may greatly affect the stereoselectivity of the HAD reaction with this donor.Entities:
Keywords: Glycosylation; Oligosaccharides; Stereoselectivity; Synthesis
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Year: 2018 PMID： 30286335 PMCID： PMC6215728 DOI： 10.1016/j.carres.2018.09.003
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104