Literature DB >> 3028588

Treatment of cytomegalovirus retinitis in a patient with AIDS with 9-(1,3-dihydroxy-2-propoxymethyl)guanine.

E A Macdonald.   

Abstract

Asymptomatic retinal lesions were found on annual ophthalmic examination in a 38-year-old homosexual man with the acquired immune deficiency syndrome (AIDS). The lesions were compatible with cytomegalovirus retinitis and progressed. Treatment with 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG) resulted in regression of the lesions and improvement in his overall clinical condition. The retinal lesions in AIDS are reviewed.

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Year:  1987        PMID： 3028588

Source DB:  PubMed          Journal:  Can J Ophthalmol        ISSN： 0008-4182            Impact factor:   1.882


  3 in total

1.  Long term therapy of cytomegalovirus retinitis with ganciclovir in a child with acquired immunodeficiency syndrome.

Authors:  S A Halperin; G R La Roche
Journal:  Can J Infect Dis       Date:  1993-01

Review 2.  Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections.

Authors:  D Faulds; R C Heel
Journal:  Drugs       Date:  1990-04       Impact factor: 9.546

Review 3.  Ocular complications of the acquired immunodeficiency syndrome. Focus on the treatment of cytomegalovirus retinitis with ganciclovir and foscarnet.

Authors:  W J Keijer; D M Burger; G H Neuteboom; J L Vrooland; P L Meenhorst; C H Koks; J H Beijnen
Journal:  Pharm World Sci       Date:  1993-04-23
  3 in total

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