| Literature DB >> 3028565 |
Abstract
Ascending noradrenergic projections from locus coeruleus reaching the rat olfactory bulb (OB) synapse onto gamma-aminobutyric acid (GABA)-ergic interneurons. We tested the hypothesis that these interneurons could locally modulate noradrenaline (NA) release. On superfused OB slices, GABA (10, 100 and 1000 microM) enhanced potassium-evoked release of newly accumulated [3H]NA. This raises the possibility that GABAergic interneurons could establish a functional link between olfactory deutoneuron activity and NA release in the rat OB.Entities:
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Year: 1987 PMID： 3028565 DOI： 10.1016/0006-8993(87)90663-9
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252