Literature DB >> 30284838

Pd-Catalyzed Alkylation of (Iso)quinolines and Arenes: 2-Acylpyridine Compounds as Alkylation Reagents.

Qingsong Wu1, Shuaijun Han1, Xiaoxiao Ren1, Hongtao Lu1, Jingya Li2, Dapeng Zou1, Yangjie Wu1, Yusheng Wu1,2,3.   

Abstract

The first Pd-catalyzed alkylation of (iso)quinolines and arenes is reported. The readily available and bench-stable 2-acylpyridine compounds were used as an alkylation reagent to form the structurally versatile alkylated (iso)quinolines and arenes. The method affords a convenient pathway for the introduction of alkyl groups into organic molecules.

Entities:  

Year:  2018        PMID: 30284838     DOI: 10.1021/acs.orglett.8b02498

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Mg3N2-assisted one-pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridine.

Authors:  Suhas G Patil; Jagannath S Jadhav; Sagar T Sankpal
Journal:  RSC Adv       Date:  2020-03-23       Impact factor: 4.036

2.  Palladium-catalyzed nucleomethylation of alkynes for synthesis of methylated heteroaromatic compounds.

Authors:  Xi Yang; Gang Wang; Zhi-Shi Ye
Journal:  Chem Sci       Date:  2022-08-18       Impact factor: 9.969

  2 in total

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