Literature DB >> 30284507

EXPRESS: Gremlin1 blocks vascular endothelial growth factor signalling in the pulmonary microvascular endothelium.

Simon Coyle Rowan, Lucie Piouceau1, Joanna Cornwell1, Lili Li1, Paul McLoughlin1.   

Abstract

Entities:  

Year:  2018        PMID： 30284507      PMCID： PMC7066471          DOI： 10.1177/2045894018807205

Source DB:  PubMed          Journal:  Pulm Circ        ISSN： 2045-8932            Impact factor:   3.017


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  75 in total

Review 1.  Pulmonary hypertension and right heart failure in chronic obstructive pulmonary disease.

Authors:  Robert Naeije
Journal:  Proc Am Thorac Soc       Date:  2005

2.  Phosphorylation of blood vessel vasodilator-stimulated phosphoprotein at serine 239 as a functional biochemical marker of endothelial nitric oxide/cyclic GMP signaling.

Authors:  César Ibarra-Alvarado; Jan Galle; Volker O Melichar; Alexander Mameghani; Harald H H W Schmidt
Journal:  Mol Pharmacol       Date:  2002-02       Impact factor: 4.436

3.  Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- Mice.

Authors:  Iris Müller; Tanja Schönberger; Martina Schneider; Oliver Borst; Melanie Ziegler; Peter Seizer; Christoph Leder; Karin Müller; Michael Lang; Florian Appenzeller; Oleg Lunov; Berthold Büchele; Manuela Fahrleitner; Marcus Olbrich; Harald Langer; Tobias Geisler; Florian Lang; Madhumita Chatterjee; Jan Freark de Boer; Uwe J F Tietge; Jürgen Bernhagen; Thomas Simmet; Meinrad Gawaz
Journal:  J Biol Chem       Date:  2013-09-03       Impact factor: 5.157

4.  Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival.

Authors:  Tero-Pekka Alastalo; Molong Li; Vinicio de Jesus Perez; David Pham; Hirofumi Sawada; Jordon K Wang; Minna Koskenvuo; Lingli Wang; Bruce A Freeman; Howard Y Chang; Marlene Rabinovitch
Journal:  J Clin Invest       Date:  2011-08-08       Impact factor: 14.808

5.  Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.

Authors:  S Dimmeler; I Fleming; B Fisslthaler; C Hermann; R Busse; A M Zeiher
Journal:  Nature       Date:  1999-06-10       Impact factor: 49.962

6.  Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

Authors:  Kwon-Ho Hong; Young Jae Lee; Eunji Lee; Sung Ok Park; Chul Han; Hideyuki Beppu; En Li; Mohan K Raizada; Kenneth D Bloch; S Paul Oh
Journal:  Circulation       Date:  2008-07-28       Impact factor: 29.690

7.  Mapping the heparin-binding site of the BMP antagonist gremlin by site-directed mutagenesis based on predictive modelling.

Authors:  Arnold Junior Tatsinkam; Barbara Mulloy; Christopher C Rider
Journal:  Biochem J       Date:  2015-06-11       Impact factor: 3.857

8.  Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension.

Authors:  Jarrod W Barnes; Elif T Kucera; Liping Tian; Noël E Mellor; Nina Dvorina; William W Baldwin; Micheala A Aldred; Carol F Farver; Suzy A A Comhair; Metin Aytekin; Raed A Dweik
Journal:  Am J Respir Cell Mol Biol       Date:  2016-10       Impact factor: 6.914

9.  Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.

Authors:  W Steudel; M Scherrer-Crosbie; K D Bloch; J Weimann; P L Huang; R C Jones; M H Picard; W M Zapol
Journal:  J Clin Invest       Date:  1998-06-01       Impact factor: 14.808

10.  Treatment with anti-gremlin 1 antibody ameliorates chronic hypoxia/SU5416-induced pulmonary arterial hypertension in mice.

Authors:  Loredana Ciuclan; Kellyann Sheppard; Liqun Dong; Daniel Sutton; Nicholas Duggan; Martin Hussey; Jenny Simmons; Nicholas W Morrell; Gabor Jarai; Matthew Edwards; Gerald Dubois; Matthew Thomas; Gino Van Heeke; Karen England
Journal:  Am J Pathol       Date:  2013-11       Impact factor: 4.307
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  3 in total

1.  No evidence of Gremlin1-mediated activation of VEGFR2 signaling in endothelial cells.

Authors:  Louise R Dutton; Christina L O'Neill; Reinhold J Medina; Derek P Brazil
Journal:  J Biol Chem       Date:  2019-10-11       Impact factor: 5.157

2.  Production and Biochemical Characterization of Dimeric Recombinant Gremlin-1.

Authors:  Stefania Mitola; Cosetta Ravelli; Michela Corsini; Alessandra Gianoncelli; Federico Galvagni; Kurt Ballmer-Hofer; Marco Presta; Elisabetta Grillo
Journal:  Int J Mol Sci       Date:  2022-01-21       Impact factor: 5.923

Review 3.  Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and Progression.

Authors:  Noha Mousaad Elemam; Abdullah Imadeddin Malek; Esraa Elaraby Mahmoud; Waseem El-Huneidi; Iman M Talaat
Journal:  Biomedicines       Date:  2022-01-28
  3 in total

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