C Calderon1, A Carmona-Bayonas2, C Beato3, I Ghanem4, R Hernandez5, M Majem6, A Rosa Diaz5, O Higuera4, M Mut Lloret7, P Jimenez-Fonseca8. 1. Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Barcelona, Barcelona, Spain. 2. Department of Hematology and Medical Oncology, Hospital Universitario Morales Meseguer, UMU, IMIB, Murcia, Spain. 3. Department of Medical Oncology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain. 4. Department of Medical Oncology, Hospital Universitario La Paz, Madrid, Spain. 5. Department of Medical Oncology, Hospital Universitario de Canarias, Tenerife, Spain. 6. Department of Medical Oncology, Hospital Universitari Santa Creu i Sant Pau, Barcelona, Spain. 7. Department of Medical Oncology, Hospital Universitario Son Espases, Mallorca, Spain. 8. Department of Medical Oncology, Hospital Universitario Central de Asturias, Oviedo, Spain. palucaji@hotmail.com.
Abstract
INTRODUCTION: This study analyzes the prevalence of malnutrition, depression, anxiety, and somatization and which factor has the biggest effect on quality of life (QoL) in individuals with resected cancer. METHODS: A prospective study was conducted among 747 participants. Participants completed the EORTC-QLQ30, MST, and BSI-18 questionnaires. RESULTS: Prevalence for risk of malnutrition, depression, anxiety, and somatization were 36.4%, 35.5%, 35.2%, and 48.8%, respectively. Hierarchical multiple regression analyses revealed that malnutrition risk, somatization, depression, and anxiety accounted for 50.8% of the variance in functional scale, 45.3% in symptom scale, and 52.2% in global health. Malnutrition, somatization, depression, and anxiety displayed high explanatory power on all health-related QoL (HRQoL) scales. CONCLUSION: The risk of malnutrition and psychological symptoms is strongly associated with HRQoL in cancer patients; thus, medical oncologists should develop effective interventions that contribute to lowering the risk of malnutrition and psychological distress, thereby improving subjects' HRQoL before initiating adjuvant chemotherapy.
INTRODUCTION: This study analyzes the prevalence of malnutrition, depression, anxiety, and somatization and which factor has the biggest effect on quality of life (QoL) in individuals with resected cancer. METHODS: A prospective study was conducted among 747 participants. Participants completed the EORTC-QLQ30, MST, and BSI-18 questionnaires. RESULTS: Prevalence for risk of malnutrition, depression, anxiety, and somatization were 36.4%, 35.5%, 35.2%, and 48.8%, respectively. Hierarchical multiple regression analyses revealed that malnutrition risk, somatization, depression, and anxiety accounted for 50.8% of the variance in functional scale, 45.3% in symptom scale, and 52.2% in global health. Malnutrition, somatization, depression, and anxiety displayed high explanatory power on all health-related QoL (HRQoL) scales. CONCLUSION: The risk of malnutrition and psychological symptoms is strongly associated with HRQoL in cancerpatients; thus, medical oncologists should develop effective interventions that contribute to lowering the risk of malnutrition and psychological distress, thereby improving subjects' HRQoL before initiating adjuvant chemotherapy.
Authors: Francisco José Sánchez-Torralvo; Victoria Contreras-Bolívar; María Ruiz-Vico; José Abuín-Fernández; Inmaculada González-Almendros; Manuel Barrios; Gabriel Olveira Journal: Support Care Cancer Date: 2021-09-21 Impact factor: 3.359
Authors: Mira Sonneborn-Papakostopoulos; Clara Dubois; Viktoria Mathies; Mara Heß; Nicole Erickson; Thomas Ernst; Jutta Huebner Journal: Med Oncol Date: 2021-02-04 Impact factor: 3.064
Authors: Paolo Cotogni; Federico Bozzetti; François Goldwasser; Paula Jimenez-Fonseca; Sine Roelsgaard Obling; Juan W Valle Journal: Ther Adv Med Oncol Date: 2022-09-26 Impact factor: 5.485