Literature DB >> 30283953

Iodine-mediated regio- and stereoselective iodothiocyanation of alkynes in aqueous ethanol.

Xianghua Zeng1, Lu Chen2.   

Abstract

Iodothiocyanation of alkynes with ammonium thiocyanate (NH4SCN) and molecular iodine (I2) has been demonstrated in aqueous ethanol, which enables efficient synthesis of a series of functional β-iodo vinylthiocyanates in good to excellent yields under mild reaction conditions without the need for any protection.

Entities:  

Year:  2018        PMID： 30283953     DOI： 10.1039/c8ob02216j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  PhICl2-Mediated Regioselective and Electrophilic Oxythio/Selenocyanation of o-(1-Alkynyl)benzoates: Access to Biologically Active S/SeCN-Containing Isocoumarins.

Authors:  Shanqing Tao; Aiwen Huo; Yan Gao; Xiangyang Zhang; Jingyue Yang; Yunfei Du
Journal:  Front Chem       Date:  2022-05-18       Impact factor: 5.545

Review 2.  Direct cyanation, hydrocyanation, dicyanation and cyanofunctionalization of alkynes.

Authors:  Lifen Peng; Zhifang Hu; Hong Wang; Li Wu; Yinchun Jiao; Zilong Tang; Xinhua Xu
Journal:  RSC Adv       Date:  2020-03-10       Impact factor: 4.036

3.  Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH4SCN and N-thiosuccinimides.

Authors:  Liang Qi; Shiwen Liu; Linxia Xiao
Journal:  RSC Adv       Date:  2020-09-10       Impact factor: 4.036
  3 in total

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