Sheraz Ali1, Oluwaseun Egunsola2, Dalal Salem Al-Dossari3, Ibrahim Abdulaziz Al-Zaagi3. 1. King Saud Medical City, Ministry of Health, Al Imam Turki Ibn Abdullah Ibn Muhammad, Ulaishah, 12746, Riyadh, Saudi Arabia. 2. Clinical Pharmacology and Toxicology Research Group, Discipline of Pharmacology, School of Medical Sciences, Sydney Medical School, The University of Sydney, NSW, Australia. 3. King Saud Medical City, Riyadh, Saudi Arabia.
Abstract
BACKGROUND: Underreporting is a common problem with spontaneous adverse drug reaction (ADR) reporting. In this study, we aim to describe the reporting of ADRs in a tertiary hospital and determine the effect of incentives to healthcare professionals on ADR reporting. METHODS: In this interventional study, a time series analysis was used to determine the effect of incentives on ADR reporting in a tertiary hospital between 2015 and 2016. The incentive strategy included public commendation of health care providers and nomination for a monthly award. RESULTS: A total of 967 ADRs were reported over a 2-year period. After the introduction of incentives in January 2016, the number of ADR reports per month increased by 40.6 (95% confidence interval: 26.1-55.1). The proportion of serious ADRs reported was significantly higher in 2016 (39/800) than 2015 (0/167) (p < 0.001). In 2016, there was a significant association between profession and serious ADR reporting (p < 0.001). A total of 14/21 ADRs (66.7%) reported by physicians in 2016 were serious compared with 20/700 (2.9%) reported by clinical pharmacists and 5/72 (6.9%) by nurses. CONCLUSIONS: ADR reporting was improved by providing incentives, including commendation and reward, to healthcare professionals.
BACKGROUND: Underreporting is a common problem with spontaneous adverse drug reaction (ADR) reporting. In this study, we aim to describe the reporting of ADRs in a tertiary hospital and determine the effect of incentives to healthcare professionals on ADR reporting. METHODS: In this interventional study, a time series analysis was used to determine the effect of incentives on ADR reporting in a tertiary hospital between 2015 and 2016. The incentive strategy included public commendation of health care providers and nomination for a monthly award. RESULTS: A total of 967 ADRs were reported over a 2-year period. After the introduction of incentives in January 2016, the number of ADR reports per month increased by 40.6 (95% confidence interval: 26.1-55.1). The proportion of serious ADRs reported was significantly higher in 2016 (39/800) than 2015 (0/167) (p < 0.001). In 2016, there was a significant association between profession and serious ADR reporting (p < 0.001). A total of 14/21 ADRs (66.7%) reported by physicians in 2016 were serious compared with 20/700 (2.9%) reported by clinical pharmacists and 5/72 (6.9%) by nurses. CONCLUSIONS: ADR reporting was improved by providing incentives, including commendation and reward, to healthcare professionals.
Entities:
Keywords:
Middle-East; drug safety; pharmacovigilance
Authors: C A Naranjo; U Busto; E M Sellers; P Sandor; I Ruiz; E A Roberts; E Janecek; C Domecq; D J Greenblatt Journal: Clin Pharmacol Ther Date: 1981-08 Impact factor: 6.875
Authors: Hisham Aljadhey; Abdulaziz Alhossan; Khalid Alburikan; Mansour Adam; Michael D Murray; David W Bates Journal: Saudi Pharm J Date: 2012-08-08 Impact factor: 4.330
Authors: Hisham Aljadhey; Mansour A Mahmoud; Yusuf Ahmed; Razia Sultana; Salah Zouein; Sulafah Alshanawani; Ahmed Mayet; Mashael K Alshaikh; Nora Kalagi; Esraa Al Tawil; Abdul Rahman El Kinge; Abdulmajid Arwadi; Maha Alyahya; Michael D Murray; David Bates Journal: BMJ Open Date: 2016-07-12 Impact factor: 2.692
Authors: Khaja Moinuddin; Sheraz Ali; Amal Qadri Al-Aqqad; Sara Osama Salem; Maram Abdullah Al-Dossari; Abdullah Mohammad Ananzeh; Jaffer Bin Baqar Journal: J Pharm Bioallied Sci Date: 2018 Jan-Mar
Authors: Paul N Deslandes; Robert Bracchi; Karen Jones; Kath E Haines; Emma Carey; Alana Adams; Jenna Walker; Alison Thomas; Philip A Routledge Journal: Br J Clin Pharmacol Date: 2022-04-07 Impact factor: 3.716