Literature DB >> 30282534

Novel Unidirectional Porous β-Tricalcium Phosphate Used as a Bone Substitute after Excision of Benign Bone Tumors of the Hand: A Case Series.

Akira Ikumi1, Toru Funayama1, Toshinori Tsukanishi2, Hiroshi Noguchi1, Masashi Yamazaki1.   

Abstract

Unidirectional porous β-tricalcium phosphate (UDPTCP; Affinos®, Kuraray, Tokyo, Japan) has been in clinical use since 2015. Animal studies have confirmed the excellent potential of UDPTCP with regard to bone formation and material absorption. We present the first three clinical cases using UDPTCP as a bone substitute after curettage of benign bone tumors of the hand. All three patients were males, 29-, 30- and 81-years-old, two having a diagnosis of enchondroma and the other, a bone ganglion, with a pathological fracture identified in one case. Over a mean follow-up of 10 months, all patients achieved satisfactory clinical result, with no adverse events of UDPTCP noted. Radiographic evidence of good bone formation and material absorption was observable over the postoperative course. UDPTCP provided satisfactory clinical results, with good biocompatibility and fast resorption characteristics. Therefore, UDPTCP could provide a safe and reliable filling substitute for bone defects following curettage of small bone tumors.

Entities:  

Keywords:  Benign bone tumor; Bone substitute; Unidirectional porous structure; β-tricalcium phosphate

Mesh:

Substances:

Year:  2018        PMID: 30282534     DOI: 10.1142/S2424835518720293

Source DB:  PubMed          Journal:  J Hand Surg Asian Pac Vol


  8 in total

1.  A Novel Unidirectional Porous β-tricalcium Phosphate Bone Substitute in Orthopedic Surgery: A Technical Note and Case Illustrations.

Authors:  Toru Funayama; Hiroshi Noguchi; Hiroshi Kumagai; Tomokazu Yoshioka; Masashi Yamazaki
Journal:  Cureus       Date:  2020-03-30

2.  Use of unidirectional and spherical porous β-tricalcium phosphate in opening-wedge high tibial osteotomy: a case series.

Authors:  Naoya Kikuchi; Tomokazu Yoshioka; Yu Taniguchi; Akihiro Kanamori; Masashi Yamazaki
Journal:  J Rural Med       Date:  2021-01-05

3.  Comparison of concentrated fresh mononuclear cells and cultured mesenchymal stem cells from bone marrow for bone regeneration.

Authors:  Fengzhou Du; Qian Wang; Long Ouyang; Huanhuan Wu; Zhigang Yang; Xin Fu; Xia Liu; Li Yan; Yilin Cao; Ran Xiao
Journal:  Stem Cells Transl Med       Date:  2020-12-19       Impact factor: 6.940

4.  A clinical trial of a unidirectional porous tricalcium phosphate filling for defects after resection of benign bone lesions: a prospective multicenter study.

Authors:  Kunihiro Ikuta; Yoshihiro Nishida; Takehiro Ota; Satoshi Tsukushi; Eiji Kozawa; Hiroatsu Nakashima; Kenji Yamada; Satoshi Yamashita; Shiro Imagama
Journal:  Sci Rep       Date:  2022-09-26       Impact factor: 4.996

5.  Effects of Strontium-Doped β-Tricalcium Scaffold on Longitudinal Nuclear Factor-Kappa Beta and Vascular Endothelial Growth Factor Receptor-2 Promoter Activities during Healing in a Murine Critical-Size Bone Defect Model.

Authors:  Mersedeh Tohidnezhad; Yusuke Kubo; Philipp Lichte; Tobias Heigl; Diana Roch; Nazanin Barahmand Pour; Christian Bergmann; Tolga Taha Sönmez; Jennifer Vanessa Phi Hock; Athanassios Fragoulis; Felix Gremse; Stefanie Rosenhain; Alexander Slowik; Michaela Bienert; Nisreen Kweider; Christoph Jan Wruck; Holger Jahr; Frank Hildebrand; Hans Christoph Pape; Sabine Neuß; Horst Fischer; Thomas Pufe
Journal:  Int J Mol Sci       Date:  2020-05-01       Impact factor: 5.923

6.  A Novel Unidirectional Porous β-tricalcium Phosphate Grafting Impregnated with Bone Marrow Blood Collected from Unfractured Vertebral Bodies for Non-union of Osteoporotic Vertebral Fracture: A Preliminary Case Report.

Authors:  Toru Funayama; Hiroshi Noguchi; Kentaro Mataki; Masashi Yamazaki
Journal:  J Orthop Case Rep       Date:  2020

7.  A novel unidirectional porous β-tricalcium phosphate grafting for vertebral fracture in the elderly: preliminary case series.

Authors:  Toru Funayama; Toshinori Tsukanishi; Hiroshi Kumagai; Hiroshi Noguchi; Shigeo Izawa; Tetsuya Abe; Kousei Miura; Katsuya Nagashima; Kentaro Mataki; Yosuke Shibao; Kosuke Sato; Masao Koda; Masashi Yamazaki
Journal:  J Rural Med       Date:  2019-11-20

8.  A radiological study of bone remodeling with two different types of porous β-tricalcium phosphate in humans.

Authors:  Naoya Kikuchi; Tomokazu Yoshioka; Norihito Arai; Kojiro Hyodo; Akihiro Kanamori; Masashi Yamazaki
Journal:  Sci Rep       Date:  2020-11-16       Impact factor: 4.379

  8 in total

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