Literature DB >> 30282530

Proceedings of the 2018 National Toxicology Program Satellite Symposium.

Susan A Elmore1, Vinicius Carreira2, Caralyn S Labriola3, Debabrata Mahapatra4, Sean R McKeag5, Matthias Rinke6, Cynthia Shackelford7, Bhanu Singh8, Ashley Talley9, Shannon M Wallace10, Lyn M Wancket11, Cynthia J Willson4.   

Abstract

The 2018 annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri," was held in Indianapolis, Indiana, at the Society of Toxicologic Pathology's 37th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks along with select images that were used by the audience for voting and discussion. Various lesions and other topics covered during the symposium included seminiferous tubule dysgenesis in rats, ameloblast and odontoblast degeneration/necrosis in a Sprague Dawley rat, intestinal leiomyositis in a beagle dog, gallbladder mucinous hyperplasia, focus of hepatocellular alteration and bile duct alteration in otters, renal tubule cytoplasmic vacuolation with basophilic granules in mice treated swith antisense oligonucleotide therapy, a uterine choriocarcinoma in a rhesus macaque, and rete ovarii proliferative ovarian lesions in various aged rat strains. One particularly provocative lesion was a malignant neoplastic proliferation in the renal pelvic region of a cynomolgus macaque from a 21-day study. Additional challenging lesions included thyroid proliferative lesions in zebra fish and gross findings in fish larvae during routine chemical screening. The Rabbit and Minipig International Harmonization of Nomenclature and Diagnostic Criteria Organ Working Groups also presented a series of challenging lesions.

Entities:  

Keywords:  INHAND; NTP Satellite Symposium; ameloblast degeneration; fish larvae gross lesions; gallbladder mucinous hyperplasia; intestinal leiomyositis; renal neoplasia; renal tubule basophilic granules; rete ovarii hyperplasia; testis dysgenesis; uterine choriocarcinoma

Mesh:

Year:  2018        PMID: 30282530      PMCID: PMC6298844          DOI: 10.1177/0192623318800734

Source DB:  PubMed          Journal:  Toxicol Pathol        ISSN: 0192-6233            Impact factor:   1.902


  96 in total

1.  The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat.

Authors:  L G Parks; J S Ostby; C R Lambright; B D Abbott; G R Klinefelter; N J Barlow; L E Gray
Journal:  Toxicol Sci       Date:  2000-12       Impact factor: 4.849

Review 2.  Gelatinous transformation of the bone marrow: the spectrum of underlying diseases.

Authors:  J Böhm
Journal:  Am J Surg Pathol       Date:  2000-01       Impact factor: 6.394

3.  Histological Development of Male Reproductive Organs in Microminipigs.

Authors:  Akihisa Kangawa; Masayoshi Otake; Satoko Enya; Toshinori Yoshida; Masatoshi Shibata
Journal:  Toxicol Pathol       Date:  2016-10-23       Impact factor: 1.902

4.  The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish.

Authors:  Sonya M Billiard; Alicia R Timme-Laragy; Deena M Wassenberg; Crystal Cockman; Richard T Di Giulio
Journal:  Toxicol Sci       Date:  2006-05-09       Impact factor: 4.849

5.  Acute and protracted effects of vinblastine on odontoblasts and dentinogenesis in rat incisors.

Authors:  H B Mikkelsen
Journal:  Scand J Dent Res       Date:  1978-09

6.  Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window.

Authors:  Sander van den Driesche; Karen R Kilcoyne; Ida Wagner; Diane Rebourcet; Ashley Boyle; Rod Mitchell; Chris McKinnell; Sheila Macpherson; Roland Donat; Chitranjan J Shukla; Anne Jorgensen; Ewa Rajpert-De Meyts; Niels E Skakkebaek; Richard M Sharpe
Journal:  JCI Insight       Date:  2017-03-23

7.  Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate.

Authors:  Norman J Barlow; Paul M D Foster
Journal:  Toxicol Pathol       Date:  2003 Jul-Aug       Impact factor: 1.902

8.  Non-gestational malignant placental site trophoblastic tumor of the ovary in a 4-year-old rhesus monkey.

Authors:  E Marbaix; S Defrère; K Ho Minh Duc; J-C Lousse; J-P Dehoux
Journal:  Vet Pathol       Date:  2008-05       Impact factor: 2.221

9.  Early dioxin exposure causes toxic effects in adult zebrafish.

Authors:  Tracie R Baker; Richard E Peterson; Warren Heideman
Journal:  Toxicol Sci       Date:  2013-06-28       Impact factor: 4.849

Review 10.  New Trends in Aryl Hydrocarbon Receptor Biology.

Authors:  Sonia Mulero-Navarro; Pedro M Fernandez-Salguero
Journal:  Front Cell Dev Biol       Date:  2016-05-11
View more
  2 in total

1.  Proceedings of the 2019 National Toxicology Program Satellite Symposium.

Authors:  Susan A Elmore; Mark F Cesta; Torrie A Crabbs; Kyathanahalli S Janardhan; Gregory A Krane; Debabrata Mahapatra; Erin M Quist; Matthias Rinke; George W Schaaf; Gregory S Travlos; Haoan Wang; Cynthia J Willson; Jeffrey C Wolf
Journal:  Toxicol Pathol       Date:  2019-10-23       Impact factor: 1.902

2.  Phthalate Toxicity in Rats and Its Relation to Testicular Dysgenesis Syndrome in Humans.

Authors:  Cynthia J Willson
Journal:  Toxicol Pathol       Date:  2021-09-23       Impact factor: 1.902

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.