| Literature DB >> 30282044 |
Eleanor C Fiedler1, Reuben J Shaw2.
Abstract
Emerging evidence suggests that changes to cellular metabolism can regulate epigenetic modifications to alter gene expression. Recently in Nature, Wu et al. show that the metabolic regulator AMPK can phosphorylate and thus stabilize the epigenetic modifying enzyme TET2, defining a novel signaling link between metabolism and the epigenome.Entities:
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Year: 2018 PMID： 30282044 DOI： 10.1016/j.cmet.2018.09.015
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287