Omari A Msemo1, Christentze Schmiegelow2, Birgitte B Nielsen3, Hannah Kousholt4, Louise G Grunnet5, Dirk L Christensen4, John P A Lusingu1, Sofie L Møller4, Reginald A Kavishe6, Daniel T R Minja1, Ib C Bygbjerg4. 1. National Institute for Medical Research, Tanga Centre, Tanga, Tanzania. 2. Centre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark. 3. Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark. 4. Section of Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark. 5. Department of Endocrinology, University of Copenhagen Hospital, Copenhagen, Denmark. 6. Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Abstract
OBJECTIVES: To determine risk factors of pre-hypertension and hypertension in a cohort of 1247 rural Tanzanian women before conception. METHODS: Demographic and socioeconomic data, anthropometric measurements, past medical and obstetric history and other risk factors for pre-hypertension and hypertension were collected using a structured questionnaire. Multiple logistic regression analysis was used to evaluate the associations between anthropometric indices and other risk factors of pre-hypertension and hypertension. The predictive power of different anthropometric indicators for identification of pre-hypertension and hypertension patients was determined by Receiver Operating Characteristic curves (ROC). RESULTS: The median (range) age was 28.0 (18-40) years. The age-standardised prevalences of pre-hypertension and hypertension were 37.2 (95% CI 34.0-40.6) and 8.5% (95%CI 6.7-10.8), respectively. Of hypertensive patients (n = 98), only 20 (20.4%) were aware of their condition. In multivariate analysis, increasing age, obesity and haemoglobin levels were significantly associated with pre-hypertension and hypertension. CONCLUSION: Despite a low prevalence of hypertension, over one third of the women had pre-hypertension. This poses a great challenge ahead as pre-hypertensive women may progress into hypertension as they grow older without appropriate interventions. Obesity was the single most important modifiable risk factor for pre-hypertension and hypertension.
OBJECTIVES: To determine risk factors of pre-hypertension and hypertension in a cohort of 1247 rural Tanzanian women before conception. METHODS: Demographic and socioeconomic data, anthropometric measurements, past medical and obstetric history and other risk factors for pre-hypertension and hypertension were collected using a structured questionnaire. Multiple logistic regression analysis was used to evaluate the associations between anthropometric indices and other risk factors of pre-hypertension and hypertension. The predictive power of different anthropometric indicators for identification of pre-hypertension and hypertensionpatients was determined by Receiver Operating Characteristic curves (ROC). RESULTS: The median (range) age was 28.0 (18-40) years. The age-standardised prevalences of pre-hypertension and hypertension were 37.2 (95% CI 34.0-40.6) and 8.5% (95%CI 6.7-10.8), respectively. Of hypertensivepatients (n = 98), only 20 (20.4%) were aware of their condition. In multivariate analysis, increasing age, obesity and haemoglobin levels were significantly associated with pre-hypertension and hypertension. CONCLUSION: Despite a low prevalence of hypertension, over one third of the women had pre-hypertension. This poses a great challenge ahead as pre-hypertensivewomen may progress into hypertension as they grow older without appropriate interventions. Obesity was the single most important modifiable risk factor for pre-hypertension and hypertension.
Authors: Louise Groth Grunnet; Line Hjort; Daniel Thomas Minja; Omari Abdul Msemo; Sofie Lykke Møller; Rashmi B Prasad; Leif Groop; John Lusingu; Birgitte Bruun Nielsen; Christentze Schmiegelow; Ib Christian Bygbjerg; Dirk Lund Christensen Journal: Int J Environ Res Public Health Date: 2020-04-29 Impact factor: 3.390