Literature DB >> 30279857

A unique case of ST-elevation myocardial infarction related to very late stent thrombosis.

Tatsunori Takahashi1, Hideki Okayama1, Go Hiasa1, Yukio Kazatani1.   

Abstract

A 67-year-old man was transferred to our hospital because of anterior ST elevation myocardial infarction (STEMI). He had a history of a sirolimus-eluting stent implantation from the left main to the left anterior descending coronary artery (LAD) 9 years before and had undergone laparoscopic prostatectomy 8 days before in the setting of discontinuation of dual antiplatelet therapy. Emergent coronary angiography showed total occlusion in the distal LAD that was successfully treated by aspiration alone. Optical coherence tomography (OCT) showed no vulnerable lesion from the occluded lesion to the proximal LAD. OCT demonstrated that the thrombus attached to floating struts at the left main bifurcation and non-apposed struts at the left coronary ostium partly protruding to aorta, while the other struts were covered and well-apposed. Based on OCT findings, this case of STEMI was thought to be caused by distal embolism of a thrombus that formed at the stent site before it evolved into total occlusion. <Learning objective: We demonstrated how optical coherence tomography can be essential in revealing the underlying pathology. The patient showed an unusual manifestation of ST-elevation myocardial infarction caused by distal embolism of a thrombus that formed at the sirolimus-eluting stent due to dual antiplatelet therapy discontinuation during perioperative period. Optical coherence tomography revealed very late stent thrombosis at the left coronary ostium and could elucidate the underlying mechanism.>.

Entities:  

Keywords:  Drug-eluting stent; Dual antiplatelet therapy; Optical coherence tomography

Year:  2017        PMID: 30279857      PMCID: PMC6149559          DOI: 10.1016/j.jccase.2017.09.008

Source DB:  PubMed          Journal:  J Cardiol Cases        ISSN: 1878-5409


  11 in total

1.  Very late stent thrombosis and late target lesion revascularization after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher Registry.

Authors:  Takeshi Kimura; Takeshi Morimoto; Yoshihisa Nakagawa; Kazuya Kawai; Shunichi Miyazaki; Toshiya Muramatsu; Nobuo Shiode; Masanobu Namura; Takahito Sone; Shigeru Oshima; Hideo Nishikawa; Yoshikazu Hiasa; Yasuhiko Hayashi; Masakiyo Nobuyoshi; Kazuaki Mitudo
Journal:  Circulation       Date:  2011-12-27       Impact factor: 29.690

2.  Very late coronary stent thrombosis of a newer-generation everolimus-eluting stent compared with early-generation drug-eluting stents: a prospective cohort study.

Authors:  Lorenz Räber; Michael Magro; Giulio G Stefanini; Bindu Kalesan; Ron T van Domburg; Yoshinobu Onuma; Peter Wenaweser; Joost Daemen; Bernhard Meier; Peter Jüni; Patrick W Serruys; Stephan Windecker
Journal:  Circulation       Date:  2012-02-01       Impact factor: 29.690

3.  Incidence and outcome of surgical procedures after sirolimus-eluting stent implantation: a report from the j-Cypher registry.

Authors:  Takeshi Kimura; Takaaki Isshiki; Yasuhiko Hayashi; Shigeru Oshima; Masanobu Namura; Hitoshi Nakashima; Kazuya Kawai; Takahito Sone; Ryozo Tatami; Taiichiro Meguro; Masakiyo Nobuyoshi; Kazuaki Mitsudo
Journal:  Cardiovasc Interv Ther       Date:  2009-11-13

4.  Delayed coverage in malapposed and side-branch struts with respect to well-apposed struts in drug-eluting stents: in vivo assessment with optical coherence tomography.

Authors:  Juan Luis Gutiérrez-Chico; Evelyn Regar; Eveline Nüesch; Takayuki Okamura; Joanna Wykrzykowska; Carlo di Mario; Stephan Windecker; Gerrit-Anne van Es; Pierre Gobbens; Peter Jüni; Patrick W Serruys
Journal:  Circulation       Date:  2011-07-18       Impact factor: 29.690

5.  Pathological findings at bifurcation lesions: the impact of flow distribution on atherosclerosis and arterial healing after stent implantation.

Authors:  Gaku Nakazawa; Saami K Yazdani; Aloke V Finn; Marc Vorpahl; Frank D Kolodgie; Renu Virmani
Journal:  J Am Coll Cardiol       Date:  2010-04-20       Impact factor: 24.094

6.  Optical coherence tomography findings in lesions after sirolimus-eluting stent implantation with peri-stent contrast staining.

Authors:  Takeshi Tada; Kazushige Kadota; Shingo Hosogi; Shunsuke Kubo; Masatomo Ozaki; Mitsuru Yoshino; Koshi Miyake; Haruki Eguchi; Noriyuki Ohashi; Yuki Hayakawa; Naoki Saito; Suguru Otsuru; Daiji Hasegawa; Yoshikazu Shigemoto; Seiji Habara; Masao Imai; Hiroyuki Tanaka; Yasushi Fuku; Naoki Oka; Harumi Kato; Hiroyuki Yamamoto; Satoki Fujii; Tsuyoshi Goto; Kazuaki Mitsudo
Journal:  Circ Cardiovasc Interv       Date:  2012-09-25       Impact factor: 6.546

7.  Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus- and paclitaxel-eluting stents.

Authors:  Gaku Nakazawa; Aloke V Finn; Marc Vorpahl; Elena R Ladich; Frank D Kolodgie; Renu Virmani
Journal:  J Am Coll Cardiol       Date:  2011-01-25       Impact factor: 24.094

8.  Examination of the in vivo mechanisms of late drug-eluting stent thrombosis: findings from optical coherence tomography and intravascular ultrasound imaging.

Authors:  Giulio Guagliumi; Vasile Sirbu; Giuseppe Musumeci; Robert Gerber; Giuseppe Biondi-Zoccai; Hideyuki Ikejima; Elena Ladich; Nikoloz Lortkipanidze; Aleksandre Matiashvili; Orazio Valsecchi; Renu Virmani; Gregg W Stone
Journal:  JACC Cardiovasc Interv       Date:  2012-01       Impact factor: 11.195

9.  Antiplatelet therapy discontinuation and stent thrombosis after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher Registry.

Authors:  Mariko Yano; Masahiro Natsuaki; Takeshi Morimoto; Yoshihisa Nakagawa; Kazuya Kawai; Shunichi Miyazaki; Toshiya Muramatsu; Nobuo Shiode; Masanobu Namura; Takahito Sone; Shigeru Oshima; Hideo Nishikawa; Yoshikazu Hiasa; Yasuhiko Hayashi; Masakiyo Nobuyoshi; Kazuaki Mitsudo; Takeshi Kimura
Journal:  Int J Cardiol       Date:  2015-06-18       Impact factor: 4.164

Review 10.  Vascular responses to drug eluting stents: importance of delayed healing.

Authors:  Aloke V Finn; Gaku Nakazawa; Michael Joner; Frank D Kolodgie; Erik K Mont; Herman K Gold; Renu Virmani
Journal:  Arterioscler Thromb Vasc Biol       Date:  2007-05-17       Impact factor: 8.311

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