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Literature DB >> 30277484

Sensing caspase-1 activity using activatable ¹⁹F MRI nanoprobes with improved turn-on kinetics.

Kazuki Akazawa¹, Fuminori Sugihara, Masafumi Minoshima, Shin Mizukami, Kazuya Kikuchi.

Abstract

Activatable 19F MRI nanoprobes for sensing caspase-1 activity were developed. Tandem repetition of substrate peptide sequences improved the turn-on response of nanoprobes, allowing detection of caspase-1 activity by 19F MRI. In vivo immune response was successfully imaged using the new nanoprobe.

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Year: 2018 PMID： 30277484 DOI： 10.1039/c8cc05381b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

5 in total

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Review 2. Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes.

Authors: Natacha Jugniot; Pierre Voisin; Abderrazzak Bentaher; Philippe Mellet
Journal: Contrast Media Mol Imaging Date: 2019-06-12 Impact factor: 3.161

Sensing caspase-1 activity using activatable ¹⁹F MRI nanoprobes with improved turn-on kinetics.

1. Summary of Imaging in 2020: Visualizing the Future of Healthcare with MR Imaging.

Review 2. Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes.

Review 3. Regulation of Fibrotic Processes in the Liver by ADAM Proteases.

Review 4. Perfluorocarbons-Based ¹⁹F Magnetic Resonance Imaging in Biomedicine.

5. Perfluorocarbon-Based ¹⁹ F MRI Nanoprobes for In Vivo Multicolor Imaging.

Sensing caspase-1 activity using activatable 19F MRI nanoprobes with improved turn-on kinetics.

1. Summary of Imaging in 2020: Visualizing the Future of Healthcare with MR Imaging.

Review 2. Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes.

Review 3. Regulation of Fibrotic Processes in the Liver by ADAM Proteases.

Review 4. Perfluorocarbons-Based 19F Magnetic Resonance Imaging in Biomedicine.

5. Perfluorocarbon-Based 19 F MRI Nanoprobes for In Vivo Multicolor Imaging.

Sensing caspase-1 activity using activatable ¹⁹F MRI nanoprobes with improved turn-on kinetics.

Review 4. Perfluorocarbons-Based ¹⁹F Magnetic Resonance Imaging in Biomedicine.

5. Perfluorocarbon-Based ¹⁹ F MRI Nanoprobes for In Vivo Multicolor Imaging.