Literature DB >> 30277205

Space Occupying Lesion in the Liver Caused by Hepatic Visceral Larva Migrans: A Case Report.

Kye-Yeung Park1, Hoon-Ki Park1, Hwan-Sik Hwang1, Jae-Sook Ryu2, Kyeong-Geun Lee3, Ki-Seok Jang4.   

Abstract

Visceral larva migrans (VLM) is one of the clinical syndromes of human toxocariasis. We report a case of hepatic VLM presenting preprandial malaise and epigastric discomfort in a 58-year-old woman drinking raw roe deer blood. The imaging studies of the abdomen showed a 74-mm hepatic mass featuring hepatic VLM. Anti-Toxocara canis immunoglobulin G (IgG) was observed in enzyme-linked immunosorbent assay (ELISA) and western blot. Despite anthelmintic treatment, the patient complained of newly developed cough and skin rash with severe eosinophilia. Hepatic lesion increased in size. The patient underwent an open left lobectomy of the liver. After the surgery, the patient was free of symptoms such as preprandial malaise, epigastric discomfort, cough, and skin rash. Laboratory test showed a normal eosinophilic count at postoperative 1 month, 6 months, 1 year, and 4 years. The initial optical density value of 2.55 of anti-T. canis IgG in ELISA was found to be negative (0.684) at postoperative 21 months. Our case report highlights that a high degree of clinical suspicion for hepatic VLM should be considered in a patient with a history of ingestion of raw food in the past, presenting severe eosinophilia and a variety of symptoms which reflect high worm burdens. Symptom remission, eosinophilia remission, and complete radiological resolution of lesions can be complete with surgery.

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Year:  2018        PMID: 30277205      PMCID: PMC6283475          DOI: 10.4269/ajtmh.18-0199

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  2 in total

1.  Be Careful What You Eat!

Authors:  Philip J Rosenthal
Journal:  Am J Trop Med Hyg       Date:  2019-11       Impact factor: 2.345

Review 2.  Brain food: rethinking food-borne toxocariasis.

Authors:  Sara R Healy; Eric R Morgan; Joaquin M Prada; Martha Betson
Journal:  Parasitology       Date:  2021-10-25       Impact factor: 3.234

  2 in total

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