Literature DB >> 30275610

The Ethics of Interstitial and Cesarean Scar Ectopic Pregnancies: Four Case Studies and a Review of the Literature.

Cara Buskmiller1.   

Abstract

Catholic bioethicists have extensively addressed extrauterine tubal pregnancies, which represent the great majority of ectopic pregnancies. However, additional management options have been developed for the other 7-10 percent of ectopic pregnancies. Using two cases of interstitial pregnancy and two cases of cesarean scar pregnancy (CSP) seen at a Catholic tertiary care center, this article discusses options including expectant management, systemic methotrexate, intragestational methotrexate, intragestational potassium chloride, uterine artery embolization, dilation and curettage (D&C), vasopressin use, cornuostomy, cornual wedge resection, CSP evacuation, CSP scar excision, CSP salvage, and hysterectomy. Cornual wedge resection, vasopressin use, and CSP scar excision are morally acceptable; less clearly licit are aspiration of gestational sac contents, cornuostomy, gestational excision for CSPs, and methotrexate. Certainly illicit are any techniques leading to direct abortion such as D&Cs on live embryos or fetuses, double-balloon catheter placement, and use of potassium chloride. Summary: An ectopic pregnancy is any pregnancy outside the uterus. These are dangerous because the pregnancy can burst out of its abnormal location and cause life-threatening internal bleeding. Most are in the part of the fallopian tube outside the uterus, but there are other types, including interstitial pregnancies (located in the part of the tube tunneling through the uterine wall) and cesarean scar pregnancies (buried in the uterine scar where the cut for a C-section was made). This article lists the ways that physicians prevent women from dying from interstitial and cesarean scar pregnancies and proposes which treatments are morally acceptable.

Entities:  

Keywords:  Bioethics; Cesarean scar pregnancy; Ectopic pregnancy; Indirect abortion; Interstitial pregnancy; Methotrexate; Vasopressin

Year:  2018        PMID: 30275610      PMCID: PMC6161235          DOI: 10.1177/0024363918788858

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  35 in total

1.  Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases.

Authors:  J Bouyer; J Coste; H Fernandez; J L Pouly; N Job-Spira
Journal:  Hum Reprod       Date:  2002-12       Impact factor: 6.918

2.  Vasopressin and oxytocin receptor mRNA expression during rat telencephalon development.

Authors:  Q Chen; S S Schreiber; R D Brinton
Journal:  Neuropeptides       Date:  2000 Jun-Aug       Impact factor: 3.286

Review 3.  Diagnostic criteria for nonviable pregnancy early in the first trimester.

Authors:  Peter M Doubilet; Carol B Benson; Tom Bourne; Michael Blaivas; Kurt T Barnhart; Beryl R Benacerraf; Douglas L Brown; Roy A Filly; J Christian Fox; Steven R Goldstein; John L Kendall; Edward A Lyons; Misty Blanchette Porter; Dolores H Pretorius; Ilan E Timor-Tritsch
Journal:  N Engl J Med       Date:  2013-10-10       Impact factor: 91.245

Review 4.  Cornual, interstitial, and angular pregnancies: clarifying the terms and a review of the literature.

Authors:  Elizabeth Kagan Arleo; Ersilia M DeFilippis
Journal:  Clin Imaging       Date:  2014-04-16       Impact factor: 1.605

Review 5.  Cesarean scar pregnancy is a precursor of morbidly adherent placenta.

Authors:  I E Timor-Tritsch; A Monteagudo; G Cali; A Vintzileos; R Viscarello; A Al-Khan; S Zamudio; P Mayberry; M M Cordoba; P Dar
Journal:  Ultrasound Obstet Gynecol       Date:  2014-07-31       Impact factor: 7.299

Review 6.  Systematic review: What is the best first-line approach for cesarean section ectopic pregnancy?

Authors:  Mine Kanat-Pektas; Serkan Bodur; Ozgur Dundar; Vuslat Lale Bakır
Journal:  Taiwan J Obstet Gynecol       Date:  2016-04       Impact factor: 1.705

7.  Laparoscopic management of ectopic pregnancies: a comparison between interstitial and "more distal" tubal pregnancies.

Authors:  Konstantinos Nirgianakis; Andrea Papadia; Giovanni Grandi; Brett McKinnon; Daniele Bolla; Michael D Mueller
Journal:  Arch Gynecol Obstet       Date:  2016-08-31       Impact factor: 2.344

8.  Pregnancy after uterine artery embolization for leiomyomata: the Ontario multicenter trial.

Authors:  Gaylene Pron; Eva Mocarski; John Bennett; George Vilos; Andrew Common; Leslie Vanderburgh
Journal:  Obstet Gynecol       Date:  2005-01       Impact factor: 7.661

9.  Laparoscopic management of 53 cases of cornual ectopic pregnancy.

Authors:  Selma Ng; Suttha Hamontri; Irene Chua; Bernard Chern; Anthony Siow
Journal:  Fertil Steril       Date:  2008-10-17       Impact factor: 7.329

10.  The Increasing Trend in Caesarean Section Rates: Global, Regional and National Estimates: 1990-2014.

Authors:  Ana Pilar Betrán; Jianfeng Ye; Anne-Beth Moller; Jun Zhang; A Metin Gülmezoglu; Maria Regina Torloni
Journal:  PLoS One       Date:  2016-02-05       Impact factor: 3.240

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