Literature DB >> 3027508

Molecular cloning and characterization of ARO7-OSM2, a single yeast gene necessary for chorismate mutase activity and growth in hypertonic medium.

S G Ball, R B Wickner, G Cottarel, M Schaus, C Tirtiaux.   

Abstract

The chorismate mutase structural gene, ARO7, which is necessary for both phenylalanine and tyrosine biosynthesis was cloned by complementation in yeast. Genetic analysis showed that ARO7 was identical to a gene necessary for growth in hypertonic medium, OSM2, which mapped nearby. After restriction mapping and subcloning of the plasmid, the cloned gene was used to detect mRNA levels in several growth conditions. Enzyme activities were measured in various genotypes. At our level of detection ARO7-OSM2 is a low level constitutively expressed gene.

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Year:  1986        PMID： 3027508     DOI： 10.1007/BF00430446

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  15 in total

Review 1.  Genetic mapping in yeast.

Authors:  R K Mortimer; D C Hawthorne
Journal:  Methods Cell Biol       Date:  1975       Impact factor: 1.441

2.  Deletions of the iso-1-cytochrome c and adjacent genes of yeast: discovery of the OSM1 gene controlling osmotic sensitivity.

Authors:  A Singh; F Sherman
Journal:  Genetics       Date:  1978-08       Impact factor: 4.562

3.  Genetic mapping of nonsense suppressors in yeast.

Authors:  D C Hawthorne; R K Mortimer
Journal:  Genetics       Date:  1968-12       Impact factor: 4.562

4.  Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene.

Authors:  K A Nasmyth; S I Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

5.  High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

Authors:  K Struhl; D T Stinchcomb; S Scherer; R W Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

6.  Transformation of yeast by a replicating hybrid plasmid.

Authors:  J D Beggs
Journal:  Nature       Date:  1978-09-14       Impact factor: 49.962

7.  Chromosomal genes essential for replication of a double-stranded RNA plasmid of Saccharomyces cerevisiae: the killer character of yeast.

Authors:  R B Wickner; M J Leibowitz
Journal:  J Mol Biol       Date:  1976-08-15       Impact factor: 5.469

8.  Sensitivity of tryptophan, tyrosine and phenylalanine mutants of Saccharomyces cerevisiae to phenethyl alcohol.

Authors:  J H Meade; T R Manney
Journal:  Genetics       Date:  1983-06       Impact factor: 4.562

9.  Participation of transcriptional and post-transcriptional regulatory mechanisms in the control of arginine metabolism in yeast.

Authors:  F Messenguy; E Dubois
Journal:  Mol Gen Genet       Date:  1983

10.  Plasmids controlled exclusion of the K2 killer double-stranded RNA plasmid of yeast.

Authors:  R B Wickner
Journal:  Cell       Date:  1980-08       Impact factor: 41.582
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  8 in total

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Authors:  Joanne M Kingsbury; Alan L Goldstein; John H McCusker
Journal:  Eukaryot Cell       Date:  2006-05

2.  Regulation of chorismate mutase in Saccharomyces cerevisiae.

Authors:  J F Brown; I W Dawes
Journal:  Mol Gen Genet       Date:  1990-01

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Authors:  G H Braus
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4.  In vivo catalysis of a metabolically essential reaction by an antibody.

Authors:  Y Tang; J B Hicks; D Hilvert
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-01       Impact factor: 11.205

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Authors:  T Schmidheini; P Sperisen; G Paravicini; R Hütter; G Braus
Journal:  J Bacteriol       Date:  1989-03       Impact factor: 3.490

6.  Metabolic engineering of Saccharomyces cerevisiae for hydroxytyrosol overproduction directly from glucose.

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Journal:  Microb Biotechnol       Date:  2021-10-24       Impact factor: 6.575

7.  Linking gene regulation and the exo-metabolome: a comparative transcriptomics approach to identify genes that impact on the production of volatile aroma compounds in yeast.

Authors:  Debra Rossouw; Tormod Naes; Florian F Bauer
Journal:  BMC Genomics       Date:  2008-11-07       Impact factor: 3.969

8.  Genome-wide identification for genes involved in sodium dodecyl sulfate toxicity in Saccharomyces cerevisiae.

Authors:  Chunlei Cao; Zhengfeng Cao; Peibin Yu; Yunying Zhao
Journal:  BMC Microbiol       Date:  2020-02-17       Impact factor: 3.605
  8 in total

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