Hyo Geun Choi1, Bumjung Park1, Yong Bae Ji2, Kyung Tae2, Chang Myeon Song2. 1. 1 Department of Otolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang, Korea. 2. 2 Department of Otolaryngology-Head & Neck Surgery, Hanyang University College of Medicine, Seoul, Korea.
Abstract
OBJECTIVE: The present study compared the frequency of depressive disorder in patients with thyroid cancer who had undergone thyroidectomy with the frequency in control individuals. STUDY DESIGN: Retrospective population-based cohort study. SETTING: This study used data from the Korean Health Insurance Review and Assessment Service-National Sample Cohort. SUBJECT AND METHODS: A total of 3609 participants with thyroid cancer who had undergone thyroidectomy between 2003 and 2011 were enrolled in this study and matched 1:4 with 14,436 control participants by age, sex, income, and region of residence. The cumulative incidence of postoperative depressive disorder was evaluated over a period of 10 years after the thyroidectomies and compared with the incidence in controls. Depressive disorder was diagnosed by a psychiatrist. RESULTS: The incidence of depressive disorder was significantly higher in the thyroid cancer with thyroidectomy group than in the controls up to postoperative year 1. A subgroup analysis showed the same higher incidence of depressive disorder in the thyroid cancer group than controls for up to 1 year after operations in young adult (≤44 years old), female, urban, and low-income groups. However, the incidence was elevated only in the year of the thyroidectomies themselves in middle-aged and older, rural, and high-income groups. CONCLUSION: Patients with thyroid cancer who undergo thyroidectomy have depressive disorder more frequently than normal controls. However, the frequency of depressive disorder after thyroidectomy recovers in a shorter period in middle-aged or older, high-income, and rural-dwelling patients, compared to younger, low-income, and urban-dwelling patients.
OBJECTIVE: The present study compared the frequency of depressive disorder in patients with thyroid cancer who had undergone thyroidectomy with the frequency in control individuals. STUDY DESIGN: Retrospective population-based cohort study. SETTING: This study used data from the Korean Health Insurance Review and Assessment Service-National Sample Cohort. SUBJECT AND METHODS: A total of 3609 participants with thyroid cancer who had undergone thyroidectomy between 2003 and 2011 were enrolled in this study and matched 1:4 with 14,436 control participants by age, sex, income, and region of residence. The cumulative incidence of postoperative depressive disorder was evaluated over a period of 10 years after the thyroidectomies and compared with the incidence in controls. Depressive disorder was diagnosed by a psychiatrist. RESULTS: The incidence of depressive disorder was significantly higher in the thyroid cancer with thyroidectomy group than in the controls up to postoperative year 1. A subgroup analysis showed the same higher incidence of depressive disorder in the thyroid cancer group than controls for up to 1 year after operations in young adult (≤44 years old), female, urban, and low-income groups. However, the incidence was elevated only in the year of the thyroidectomies themselves in middle-aged and older, rural, and high-income groups. CONCLUSION:Patients with thyroid cancer who undergo thyroidectomy have depressive disorder more frequently than normal controls. However, the frequency of depressive disorder after thyroidectomy recovers in a shorter period in middle-aged or older, high-income, and rural-dwelling patients, compared to younger, low-income, and urban-dwellingpatients.
Authors: Young Ju Jin; Jeong Hun Hah; Mi Jung Kwon; Ji Hee Kim; Joo-Hee Kim; Sung-Kyun Kim; Bumjung Park; Hyo Geun Choi Journal: Int J Environ Res Public Health Date: 2022-05-31 Impact factor: 4.614