Arata Oda1, Vilhelmiina Parikka2, Liisa Lehtonen2, Hanna Soukka2. 1. Department of Pediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland. Electronic address: arata-oda@nkodomo-hsp.jp. 2. Department of Pediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland; University of Turku, Turku, Finland.
Abstract
OBJECTIVE: To investigate breathing patterns during respiratory adaptation in preterm infants using the electrical activity of the diaphragm (EAdi) signal. PATIENTS: Infants born between 28 + 0 and 31 + 6 gestational weeks and supported by early nasal continuous positive airway pressure (nCPAP) were studied. The EAdi signal was recorded for 120 min after birth. RESULTS: Eight preterm infants were evaluated. The median EAdi peak value of 19.2 μV (lower quartile 13.1; upper quartile 22.2) at 20 min after birth decreased to 11.4 μV (9.5-14.7) at 55 min of age. The median EAdi minimum value of 4.5 μV (2.2-5.5) at 25 min after birth decreased to 1.6 μV (1.2-2.7) at 85 min of age. CONCLUSION: EAdi was high right after birth. This indicates that preterm infants are capable of generating sufficient respiratory drive and diaphragm tone during expiration to establish and maintain functional residual capacity. Diaphragm activity decreased within the first 90 min, suggesting that early adaptation was accomplished by 90 min of age.
OBJECTIVE: To investigate breathing patterns during respiratory adaptation in preterm infants using the electrical activity of the diaphragm (EAdi) signal. PATIENTS: Infants born between 28 + 0 and 31 + 6 gestational weeks and supported by early nasal continuous positive airway pressure (nCPAP) were studied. The EAdi signal was recorded for 120 min after birth. RESULTS: Eight preterm infants were evaluated. The median EAdi peak value of 19.2 μV (lower quartile 13.1; upper quartile 22.2) at 20 min after birth decreased to 11.4 μV (9.5-14.7) at 55 min of age. The median EAdi minimum value of 4.5 μV (2.2-5.5) at 25 min after birth decreased to 1.6 μV (1.2-2.7) at 85 min of age. CONCLUSION: EAdi was high right after birth. This indicates that preterm infants are capable of generating sufficient respiratory drive and diaphragm tone during expiration to establish and maintain functional residual capacity. Diaphragm activity decreased within the first 90 min, suggesting that early adaptation was accomplished by 90 min of age.
Authors: Ruud W van Leuteren; Anouk W J Scholten; Janneke Dekker; Tessa Martherus; Frans H de Jongh; Anton H van Kaam; Arjan B Te Pas; Jeroen Hutten Journal: Front Pediatr Date: 2021-02-09 Impact factor: 3.418