Literature DB >> 30272579

Science, serendipity, and the single degree.

Helen H Hobbs.   

Abstract

Mesh：

Year:  2018        PMID： 30272579      PMCID： PMC6159963          DOI： 10.1172/JCI124404

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  54 in total

1.  Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

Authors:  K E Berge; H Tian; G A Graf; L Yu; N V Grishin; J Schultz; P Kwiterovich; B Shan; R Barnes; H H Hobbs
Journal:  Science       Date:  2000-12-01       Impact factor: 47.728

2.  A feed-forward loop amplifies nutritional regulation of PNPLA3.

Authors:  Yongcheng Huang; Shaoqing He; John Zhong Li; Young-Kyo Seo; Timothy F Osborne; Jonathan C Cohen; Helen H Hobbs
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-12       Impact factor: 11.205

3.  TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.

Authors:  Hovsep Mahdessian; Apostolos Taxiarchis; Sergej Popov; Angela Silveira; Anders Franco-Cereceda; Anders Hamsten; Per Eriksson; Ferdinand van't Hooft
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-04       Impact factor: 11.205

4.  Transport of lipids from high and low density lipoproteins via scavenger receptor-BI.

Authors:  H Stangl; M Hyatt; H H Hobbs
Journal:  J Biol Chem       Date:  1999-11-12       Impact factor: 5.157

5.  Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial.

Authors:  Evan A Stein; Dan Gipe; Jean Bergeron; Daniel Gaudet; Robert Weiss; Robert Dufour; Richard Wu; Robert Pordy
Journal:  Lancet       Date:  2012-05-26       Impact factor: 79.321

6.  Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice.

Authors:  Thomas A Lagace; David E Curtis; Rita Garuti; Markey C McNutt; Sahng Wook Park; Heidi B Prather; Norma N Anderson; Y K Ho; Robert E Hammer; Jay D Horton
Journal:  J Clin Invest       Date:  2006-11       Impact factor: 14.808

7.  Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells.

Authors:  Markey C McNutt; Thomas A Lagace; Jay D Horton
Journal:  J Biol Chem       Date:  2007-05-29       Impact factor: 5.157

8.  Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.

Authors:  Christopher M Jenkins; David J Mancuso; Wei Yan; Harold F Sims; Beverly Gibson; Richard W Gross
Journal:  J Biol Chem       Date:  2004-09-10       Impact factor: 5.157

9.  Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis.

Authors:  Valérie Paradis; Stéphane Zalinski; Emna Chelbi; Nathalie Guedj; Françoise Degos; Valérie Vilgrain; Pierre Bedossa; Jacques Belghiti
Journal:  Hepatology       Date:  2009-03       Impact factor: 17.425

10.  Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.

Authors:  Eriks Smagris; Soumik BasuRay; John Li; Yongcheng Huang; Ka-man V Lai; Jesper Gromada; Jonathan C Cohen; Helen H Hobbs
Journal:  Hepatology       Date:  2014-10-01       Impact factor: 17.425
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  1 in total

Review 1.  TM6SF2: A Novel Genetic Player in Nonalcoholic Fatty Liver and Cardiovascular Disease.

Authors:  Fei Luo; Avash Das; Federico Oldoni
Journal:  Hepatol Commun       Date:  2021-09-16
  1 in total

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