Literature DB >> 30272215

Acute Abdomen in Pediatric Patients With Lassa Fever: Prevalence and Response to Nonoperative Management.

George O Akpede1, Adewale E Adetunji1, Ernest O Udefiagbon2, Sylvester O Eluehike3, Angela I Odike1, Rosemary O Ewah-Odiase1, Folorunso O Omosofe4, Johnbull M Akerele2, Rebecca O Atafo5, Martha O Okonofua5,6, Imonifome Onyeke1, Omobolaji A Oyedeji1, Kaine Mbanefo1, Ephraim Ogbaini-Emovon6, Peter O Okokhere7, Stephan Günther8, Andrew E Dongo2.   

Abstract

Few reports on the prevalence of acute abdomen (AAbd) in pediatric patients with Lassa fever (LF) are available, and no firm policy on its management exists. Here, we report on its prevalence in and the response to treatment among a cohort of children with confirmed LF. Six (10.3%) of 58 children with LF had AAbd, whereas 6 (2.8%) of 215 children with AAbd had LF. Nonoperative treatment was successful in 5 of the 6 children with both AAbd and LF. We conclude that AAbd is not uncommon in pediatric patients with LF, and it could be responsive to nonoperative treatment. Testing for LF in all children with febrile AAbd might be justified in areas in which LF is endemic.
© The Author(s) 2018. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Lassa fever; acute abdomen; children; comorbidity; conservative treatment

Mesh:

Year:  2019        PMID: 30272215     DOI: 10.1093/jpids/piy093

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN: 2048-7193            Impact factor:   3.164


  2 in total

1.  Clinical characterization of Lassa fever: A systematic review of clinical reports and research to inform clinical trial design.

Authors:  Laura Merson; Josephine Bourner; Sulaiman Jalloh; Astrid Erber; Alex Paddy Salam; Antoine Flahault; Piero L Olliaro
Journal:  PLoS Negl Trop Dis       Date:  2021-09-21

2.  Fatal case of newborn Lassa fever virus infection mimicking late onset neonatal sepsis: a case report from northern Nigeria.

Authors:  Taofik Oluwaseun Ogunkunle; Surajudeen Oyeleke Bello; Chinwe Immaculata Anderson; Rashida Musa; Rasaq Olaosebikan; Abdulazeez Imam
Journal:  Infect Dis Poverty       Date:  2020-08-10       Impact factor: 4.520

  2 in total

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