| Literature DB >> 30270766 |
Amir Abdoli1,2, Mohammad Barati3, Majid Pirestani4, Abdolhossein Dalimi5.
Abstract
Toxoplasmosis is an opportunistic infectious disease in immunocompromised patients, including cancer patients, whose detection is by molecular and serological methods. A total of 106 blood samples from patients with different types of cancer were evaluated for anti- Toxoplasma gondii IgG and IgM antibodies by the enzyme-linked immunosorbent assay (ELISA) and the parasite DNA by nested polymerase chain reaction (PCR). These were detected in 41.51% (44/106) and 0.94% (1/106), respectively, but T. gondii IgM antibody was not detected at all. These results suggest that the screening of toxoplasmosis should be considered more routinely in cancer patients.Entities:
Keywords: ELISA; PCR; cancer; molecular detection; serology
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Year: 2018 PMID: 30270766 DOI: 10.1177/0049475518801618
Source DB: PubMed Journal: Trop Doct ISSN: 0049-4755 Impact factor: 0.731