Amanda M Pugh1, Courtney M Giannini2, Susan M Pinney3, Dennis J Hanseman4, Elizabeth A Shaughnessy5, Jaime D Lewis5. 1. Department of Surgery Division of Research, University of Cincinnati, College of Medicine, Cincinnati, OH, 45267, United States. Electronic address: pugham@ucmail.uc.edu. 2. University of Cincinnati, College of Medicine, Cincinnati, OH, 45267, United States. 3. Department of Environmental Health, University of Cincinnati, College of Medicine, Cincinnati, OH, 45267, United States. 4. Department of Surgery Division of Research, University of Cincinnati, College of Medicine, Cincinnati, OH, 45267, United States. 5. Department of Surgery, Division of Surgical Oncology, University of Cincinnati, College of Medicine, Cincinnati, OH, 45267, United States.
Abstract
BACKGROUND: Pregnancy-associated breast cancer (PABC) is the most common malignancy in pregnancy. However due to its infrequent occurrence, PABC continues to be poorly understood. METHODS: We performed a retrospective study using self-reported data from 1079 eligible women in a regional breast cancer registry. RESULTS: The PABC cases were more likely than non-PABCs to be younger than age 35 and have nodal involvement at diagnosis. Despite diagnosis at a young age, there was not an association between PABC and family history. For method of diagnosis, PABC was found on self-exam, while non-PABCs were found on mammography. CONCLUSION: In conclusion, PABC is rarely detected by mammography and diagnosis is highly dependent on detection during self-breast exam. Women who are or recently were pregnant should be encouraged to perform regular self-breast exams to report any changes for further evaluation. Patient and clinician education regarding risk and realities of PABC is essential.
BACKGROUND: Pregnancy-associated breast cancer (PABC) is the most common malignancy in pregnancy. However due to its infrequent occurrence, PABC continues to be poorly understood. METHODS: We performed a retrospective study using self-reported data from 1079 eligible women in a regional breast cancer registry. RESULTS: The PABC cases were more likely than non-PABCs to be younger than age 35 and have nodal involvement at diagnosis. Despite diagnosis at a young age, there was not an association between PABC and family history. For method of diagnosis, PABC was found on self-exam, while non-PABCs were found on mammography. CONCLUSION: In conclusion, PABC is rarely detected by mammography and diagnosis is highly dependent on detection during self-breast exam. Women who are or recently were pregnant should be encouraged to perform regular self-breast exams to report any changes for further evaluation. Patient and clinician education regarding risk and realities of PABC is essential.
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