Literature DB >> 3026951

DNA-polymorphism of type I collagen gene detected with Bgl II in the genetically isolated Finnish population.

H Ahti, A Palotie, L Peltonen, F Ramirez.   

Abstract

The pro alpha 2(I) collagen gene has been screened for Bgl II restriction fragment length polymorphisms (RFLPs) in the Finnish population which has a long background of genetic isolation. As genetically isolated populations tend to demonstrate deviations in the degree of heterozygosity, the RFLP markers described in more heterogeneous populations can not be utilized as such in the former. This proved to be the case with Bgl II polymorphism within the pro alpha 2(I) collagen gene, the gene involved in different disorders of connective tissue. This report describes the presence of three new RFLP-loci and the absence of one RFLP-locus, which had been earlier reported from a population with a genetic background remote from the population studied here.

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Year:  1987        PMID： 3026951     DOI： 10.1007/BF00273846

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  7 in total

1.  Two new polymorphic markers in the human pro alpha 2(1) collagen gene.

Authors:  D K Brebner; A F Grobler-Rabie; A J Bester; C G Mathew; C D Boyd
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

2.  Polymorphism of DNA sequence in the human pro alpha 2(I) collagen gene.

Authors:  A F Grobler-Rabie; D K Brebner; S Vandenplas; G Wallis; R Dalgleish; R E Kaufman; A J Bester; C G Mathew; C D Boyd
Journal:  J Med Genet       Date:  1985-06       Impact factor: 6.318

3.  Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta.

Authors:  P Tsipouras; J C Myers; F Ramirez; D J Prockop
Journal:  J Clin Invest       Date:  1983-10       Impact factor: 14.808

4.  Molecular heterogeneity in the mild autosomal dominant forms of osteogenesis imperfecta.

Authors:  P Tsipouras; A L Børresen; L A Dickson; K Berg; D J Prockop; F Ramirez
Journal:  Am J Hum Genet       Date:  1984-11       Impact factor: 11.025

5.  Cloning a cDNA for the pro-alpha 2 chain of human type I collagen.

Authors:  J C Myers; M L Chu; S H Faro; W J Clark; D J Prockop; F Ramirez
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

6.  Osteogenesis imperfecta is linked to both type I collagen structural genes.

Authors:  B Sykes; D Ogilvie; P Wordsworth; N Jones
Journal:  Lancet       Date:  1986-07-12       Impact factor: 79.321

7.  Detection of a high frequency RsaI polymorphism in the human pro alpha 2(I) collagen gene which is linked to an autosomal dominant form of osteogenesis imperfecta.

Authors:  A F Grobler-Rabie; G Wallis; D K Brebner; P Beighton; A J Bester; C G Mathew
Journal:  EMBO J       Date:  1985-07       Impact factor: 11.598
  7 in total
  2 in total

1.  BglII RFLPs in the COL1A2 gene in the Finnish population.

Authors:  H Ahti; A Palotie; L Peltonen
Journal:  Hum Genet       Date:  1988-09       Impact factor: 4.132

2.  Bgl II RFLPs in the COL1A2 gene in the Finnish population. A comment.

Authors:  R Dalgleish
Journal:  Hum Genet       Date:  1988-01       Impact factor: 4.132
  2 in total

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