Jie Chen1, Chao-Min Wan2, Si-Tang Gong3, Feng Fang4, Mei Sun5, Yuan Qian6, Ying Huang7, Bao-Xi Wang8, Chun-Di Xu9, Li-Yan Ye10, Mei Dong11, Yu Jin12, Zhi-Hua Huang4, Qin-Bing Wu13, Chao-Min Zhu14, You-Hong Fang15, Qi-Rong Zhu16, Yong-Sui Dong3. 1. Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310051, China. hzcjie@zju.edu.cn. 2. Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, 610041, China. 3. Department of Gastroenterology, Guangzhou Women and Children's Medical Center, Guangzhou, 510623, China. 4. Department of Pediatrics, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. 5. Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, 110004, China. 6. Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, 100020, China. 7. Department of Gastroenterology, Children's Hospital of Fudan University, Shanghai 201102, China. 8. Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xi'an, 710038, China. 9. Department of Pediatrics, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 350025, China. 10. Department of Pediatrics, Fuzhou East Hospital, Fuzhou, 350025, China. 11. Department of Pediatrics, Peking Union Medical College Hospital, Beijing, 100730, China. 12. Department of Gastroenterology, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China. 13. Department of Gastroenterology, Children's Hospital of Soochow University, Suzhou, 215003, China. 14. Department of Infectious Diseases, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China. 15. Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310051, China. 16. Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, 201102, China.
Abstract
BACKGROUND: The guidelines addressed the evidence-based indications for the management of children with acute infectious diarrhea in Chinese pediatric population. DATA SOURCES: The experts group of evidence development put forward clinical problems, collects evidence, forms preliminary recommendations, and then uses open-ended discussions to form recommendations. The literature review was done for developing this guideline in databases including PubMed, Cochrane, EMBASE, China Biomedical Database, and Chinese Journal Full-text Database up to June 2013. Search the topic "acute diarrhea" or "enteritis" and "adolescent" or "child" or "Pediatric patient" or "Baby" or "Infant". RESULTS: For the treatment of mild, moderate dehydration, hypotonic oral rehydration solutions (ORS) are strongly recommended. Intravenous (IV) rehydration is recommended for severe dehydration, with a mixture of alkali-containing dextrose sodium solution. Nasogastric feeding tube rehydration is used for children with severe dehydration without IV infusion conditions with ORS solution. Regular feeding should resume as soon as possible after oral rehydration or IV rehydration. The lactose-free diet can shorten the diarrhea duration. Zinc supplements are recommended in children with acute infectious diarrhea. Saccharomyces boulardii and Lactobacillus Rhamnus are recommended to be used in acute watery diarrhea. Saccharomyces boulardii is recommended in children with antibiotic-associated diarrhea as well. Montmorillonite and Racecadotril (acetorphan) can improve the symptoms of diarrhea or shorten the course of acute watery diarrhea. Antibiotics are recommended with dysenteric-like diarrhea, suspected cholera with severe dehydration, immunodeficiency, and premature delivery children with chronic underlying disease; otherwise, antibiotics are not recommended. CONCLUSION: The principles of the most controversial treatments with of acute infectious disease are reaching to a consensus in China.
BACKGROUND: The guidelines addressed the evidence-based indications for the management of children with acute infectious diarrhea in Chinese pediatric population. DATA SOURCES: The experts group of evidence development put forward clinical problems, collects evidence, forms preliminary recommendations, and then uses open-ended discussions to form recommendations. The literature review was done for developing this guideline in databases including PubMed, Cochrane, EMBASE, China Biomedical Database, and Chinese Journal Full-text Database up to June 2013. Search the topic "acute diarrhea" or "enteritis" and "adolescent" or "child" or "Pediatric patient" or "Baby" or "Infant". RESULTS: For the treatment of mild, moderate dehydration, hypotonic oral rehydration solutions (ORS) are strongly recommended. Intravenous (IV) rehydration is recommended for severe dehydration, with a mixture of alkali-containing dextrose sodium solution. Nasogastric feeding tube rehydration is used for children with severe dehydration without IV infusion conditions with ORS solution. Regular feeding should resume as soon as possible after oral rehydration or IV rehydration. The lactose-free diet can shorten the diarrhea duration. Zinc supplements are recommended in children with acute infectious diarrhea. Saccharomyces boulardii and Lactobacillus Rhamnus are recommended to be used in acute watery diarrhea. Saccharomyces boulardii is recommended in children with antibiotic-associated diarrhea as well. Montmorillonite and Racecadotril (acetorphan) can improve the symptoms of diarrhea or shorten the course of acute watery diarrhea. Antibiotics are recommended with dysenteric-like diarrhea, suspected cholera with severe dehydration, immunodeficiency, and premature delivery children with chronic underlying disease; otherwise, antibiotics are not recommended. CONCLUSION: The principles of the most controversial treatments with of acute infectious disease are reaching to a consensus in China.
Authors: A A Madkour; E M Madina; O E el-Azzouni; M A Amer; T M el-Walili; T Abbass Journal: J Pediatr Gastroenterol Nutr Date: 1993-08 Impact factor: 2.839
Authors: Li Liu; Hope L Johnson; Simon Cousens; Jamie Perin; Susana Scott; Joy E Lawn; Igor Rudan; Harry Campbell; Richard Cibulskis; Mengying Li; Colin Mathers; Robert E Black Journal: Lancet Date: 2012-05-11 Impact factor: 79.321