| Literature DB >> 30267564 |
Silvia Bozza1, Fabian Käsermann2, Srini V Kaveri3, Luigina Romani4, Jagadeesh Bayry3.
Abstract
Intravenous immunoglobuin (IVIG) exerts protective effects in experimental allergic bronchopulmonary aspergillosis (ABPA) via a sialylation-dependent mechanism. The protection was associated with reduced recruitment of eosinophils, diminished goblet cell hyperplasia, suppressed Th2 and Th17 responses and reciprocally enhanced regulatory T cells and IL-10, and decreased IgE levels in the circulation.Entities:
Keywords: ABPA; Aspergillus fumigatus; IL-17F; IVIG; Tregs
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Year: 2018 PMID: 30267564 DOI: 10.1002/eji.201847774
Source DB: PubMed Journal: Eur J Immunol ISSN: 0014-2980 Impact factor: 5.532