| Literature DB >> 30266343 |
Ling Jiang1, Hongxin Fu2, Hopen K Yang3, Wei Xu4, Jufang Wang5, Shang-Tian Yang6.
Abstract
Butyric acid is an important C4 organic acid with broad applications. It is currently produced by chemosynthesis from petroleum-based feedstocks. However, the fermentative production of butyric acid from renewable feedstocks has received growing attention because of consumer demand for green products and natural ingredients in foods, pharmaceuticals, animal feed supplements, and cosmetics. In this review, strategies for improving microbial butyric acid production, including strain engineering and novel fermentation process development are discussed and compared regarding product yield, titer, purity and productivity. Future perspectives on strain and process improvements for butyric acid production are also discussed.Entities:
Keywords: Butyric acid; Clostridia; Fermentation; Metabolic engineering; Product recovery; Renewable feedstock
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Year: 2018 PMID: 30266343 DOI: 10.1016/j.biotechadv.2018.09.005
Source DB: PubMed Journal: Biotechnol Adv ISSN: 0734-9750 Impact factor: 14.227