Literature DB >> 30266271

Role of Zeb2/Sip1 in neuronal development.

Ekaterina Epifanova1, Alexey Babaev2, Andrew G Newman3, Victor Tarabykin4.   

Abstract

Zeb2 (Sip1, Zfhx1b) is a transcription factor that plays essential role in neuronal development. Sip1 mutation in humans was shown to cause Mowat-Wilson syndrome, a syndromic form of Hirschprung's disease. Affected individuals exhibit multiple severe neurodevelopmental defects. Zeb2 can act as both transcriptional repressor and activator. It controls expression of a wide number of genes that regulate various aspects of neuronal development. This review addresses the molecular pathways acting downstream of Zeb2 that cause brain development disorders.
Copyright © 2018. Published by Elsevier B.V.

Entities:  

Keywords:  Brain development; Cortex; Hippocampus; Mowat-Wilson syndrome

Mesh：

Substances：

Year:  2018        PMID： 30266271     DOI： 10.1016/j.brainres.2018.09.034

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  14 in total

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Authors:  Wenshuang Wang; Anli Xu; Manyin Zhao; Jianan Sun; Lingyun Gao
Journal:  Biotechnol Lett       Date:  2021-01-01       Impact factor: 2.461

2.  Zeb2 directs EMT-like processes that underlies the glial response to injury.

Authors:  Ana L Vivinetto; John W Cave
Journal:  Neural Regen Res       Date:  2021-09       Impact factor: 5.135

3.  Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury.

Authors:  Ana L Vivinetto; Il-Doo Kim; David C Goldberg; Lilah Fones; Elizabeth Brown; Victor S Tarabykin; Caitlin E Hill; Sunghee Cho; John W Cave
Journal:  Cell Rep       Date:  2020-06-30       Impact factor: 9.423

Review 4.  MicroRNAs Involved in Small-cell Lung Cancer as Possible Agents for Treatment and Identification of New Targets.

Authors:  Ulrich H Weidle; Adam Nopora
Journal:  Cancer Genomics Proteomics       Date:  2021 Sep-Oct       Impact factor: 4.069

5.  An early cell shape transition drives evolutionary expansion of the human forebrain.

Authors:  Silvia Benito-Kwiecinski; Stefano L Giandomenico; Magdalena Sutcliffe; Erlend S Riis; Paula Freire-Pritchett; Iva Kelava; Stephanie Wunderlich; Ulrich Martin; Gregory A Wray; Kate McDole; Madeline A Lancaster
Journal:  Cell       Date:  2021-03-24       Impact factor: 41.582

Review 6.  Tumor Suppressive Effects of miR-124 and Its Function in Neuronal Development.

Authors:  Rikako Sanuki; Tomonori Yamamura
Journal:  Int J Mol Sci       Date:  2021-05-31       Impact factor: 5.923

7.  A Computational Model of the Endothelial to Mesenchymal Transition.

Authors:  Nathan Weinstein; Luis Mendoza; Elena R Álvarez-Buylla
Journal:  Front Genet       Date:  2020-03-12       Impact factor: 4.599

Review 8.  Host Transcription Factors in Hepatitis B Virus RNA Synthesis.

Authors:  Kristi L Turton; Vanessa Meier-Stephenson; Maulik D Badmalia; Carla S Coffin; Trushar R Patel
Journal:  Viruses       Date:  2020-01-30       Impact factor: 5.048

9.  MicroRNA-769-3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β-catenin signaling pathway.

Authors:  Kai Wang; Shasha Yang; Yishen Gao; Caihong Zhang; Qiangbo Sui
Journal:  Oncol Lett       Date:  2019-11-21       Impact factor: 2.967

10.  A novel nonsense mutation of ZEB2 gene in a Chinese patient with Mowat-Wilson syndrome.

Authors:  Yuan Hu; Qi Peng; Keze Ma; Siping Li; Chunbao Rao; Baimao Zhong; Xiaomei Lu
Journal:  J Clin Lab Anal       Date:  2020-06-10       Impact factor: 2.352
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