Literature DB >> 30265272

The Impact of Renal Tissue Procurement at Bedside on Specimen Adequacy and Best Practices.

Jacob T Wooldridge1, Amy Davis1, Wayne G Fischer2, Mohamed F Khalil1, Min Zhang1, Marjan Afrouzian1.   

Abstract

Objectives: Renal biopsy is the gold standard for the diagnosis of both native and allograft renal diseases. We studied the impact of tissue procurement at bedside (TPB) omission on the adequacy of renal biopsies.
Methods: We compared 120 renal biopsies collected during 2015 using TPB with 111 renal biopsies collected during 2016 when TPB was discontinued. Adequacy criteria were applied as follows: by light microscopy, 10 glomeruli and two arteries for allograft biopsies and seven glomeruli for native biopsies. At least one glomerulus was considered adequate for immunofluorescence and electron microscopy in both groups.
Results: The rate of inadequacies in allograft biopsies increased significantly, from 12.50% to 21.61% (P < .05), when TPB was discontinued. Conclusions: Elimination of TPB service had a negative impact on allograft specimen adequacy. Repeat biopsies add cost and delay patient care. Institutions should take this into consideration when considering omission of TPB.

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Year:  2019        PMID: 30265272     DOI: 10.1093/ajcp/aqy120

Source DB:  PubMed          Journal:  Am J Clin Pathol        ISSN: 0002-9173            Impact factor:   2.493


  2 in total

1.  Use of a Smartphone Camera at the Bedside to Assess Adequacy of Kidney Biopsies.

Authors:  Gurmukteshwar Singh; Mark Massak; Michael Czaplicki; Evan Young; Shree Sharma; Alex Chang; Ashok Bhanushali; Prince Anand
Journal:  J Am Soc Nephrol       Date:  2021-09-13       Impact factor: 10.121

2.  Improvement of allograft kidney biopsy yield by using a handheld smartphone microscope as an on-site evaluation device.

Authors:  Wichien Sirithanaphol; Natthida Incharoen; Ukrit Rompsaithong; Pakorn Kiatsopit; Supanut Lumbiganon; Jarin Chindaprasirt
Journal:  Heliyon       Date:  2021-05-29
  2 in total

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