PURPOSE: Derivation of dose-response relationships for exposed organisms and their sensitive life history stages requires in-house experiments under well-defined, controlled conditions. In the present work we describe the FIGARO low dose gamma irradiation facility at the Norwegian University of Life Sciences, Ås, Norway, which is managed by the Centre of Environmental Radioactivity (CERAD CoE). CONCLUSIONS: The CERAD/NMBU facility opened in 2003, and was upgraded to a climate controlled facility in 2012, supported by the EU DoReMi project. The 60Co irradiation source provides a continuous dose rate field from 3 Gy/hr down to 0.4 mGy/hr when maximally loaded (400 GBq). The FIGARO low dose gamma irradiation facility allows simultaneous acute to chronic exposure of organisms over the whole dose-rate field. The facility is licensed for a number of different test organisms, including GMOs, and can be used in combination with other stressors such as trace metals and UV radiation.
PURPOSE: Derivation of dose-response relationships for exposed organisms and their sensitive life history stages requires in-house experiments under well-defined, controlled conditions. In the present work we describe the FIGARO low dose gamma irradiation facility at the Norwegian University of Life Sciences, Ås, Norway, which is managed by the Centre of Environmental Radioactivity (CERAD CoE). CONCLUSIONS: The CERAD/NMBU facility opened in 2003, and was upgraded to a climate controlled facility in 2012, supported by the EU DoReMi project. The 60Co irradiation source provides a continuous dose rate field from 3 Gy/hr down to 0.4 mGy/hr when maximally loaded (400 GBq). The FIGARO low dose gamma irradiation facility allows simultaneous acute to chronic exposure of organisms over the whole dose-rate field. The facility is licensed for a number of different test organisms, including GMOs, and can be used in combination with other stressors such as trace metals and UV radiation.
Entities:
Keywords:
Gamma irradiation facility; a series of test organisms; multiple stressor exposures; radiobiology; radioecology
Authors: Guy Garty; Yanping Xu; Gary W Johnson; Lubomir B Smilenov; Simon K Joseph; Monica Pujol-Canadell; Helen C Turner; Shanaz A Ghandhi; Qi Wang; Rompin Shih; Robert C Morton; David E Cuniberti; Shad R Morton; Carlos Bueno-Beti; Thomas L Morgan; Peter F Caracappa; Evagelia C Laiakis; Albert J Fornace; Sally A Amundson; David J Brenner Journal: Sci Rep Date: 2020-11-16 Impact factor: 4.379