Literature DB >> 30264030

Surgical management of an adult manifestation of Ewing sarcoma of the spine-a case report.

Loay Shoubash1, Stephan Nowak1, Silke Vogelgesang2, Henry W S Schroeder1, Jan-Uwe Müller1.   

Abstract

Ewing sarcoma (ES) is a primary malignant bone tumor. Its occurrence in adults is uncommon. Even rarer is the occurrence in the spine. The prognosis of this tumor in adult patients is unfavorable. In this report, we present the case of a 56-year-old woman with ES localized at the upper thoracic spine, presented with acute incomplete paraplegia. The patient underwent emergency decompressive hemilaminectomy and tumor debulking surgery to decompress the spinal cord. As adjuvant therapy, she received radio-chemotherapy followed by en bloc resection via a combined dorsoventral approach. In the course of the disease, the patient showed a continuous neurological improvement from AISA B to E over the follow up period of 18 months. To date there has been no evidence of tumor recurrence. We report our experience in treating ES of the spine in an adult patient presenting with neurological deficits. We highlight the advantage of en bloc resection of the tumor after spinal stabilization to treat the local disease and alleviating the presenting symptoms.

Entities:  

Keywords:  Ewing sarcoma (ES); en bloc resection; sarcoma of the spine

Year:  2018        PMID: 30264030      PMCID: PMC6155648          DOI: 10.21037/acr.2018.06.07

Source DB:  PubMed          Journal:  AME Case Rep        ISSN: 2523-1995


  16 in total

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Authors:  H W Hense; S Ahrens; M Paulussen; M Lehnert; H Jürgens
Journal:  Klin Padiatr       Date:  1999 Jul-Aug       Impact factor: 1.349

5.  Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.

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Journal:  N Engl J Med       Date:  2003-02-20       Impact factor: 91.245

6.  The Neurological Compromised Spine Due to Ewing Sarcoma. What First: Surgery or Chemotherapy? Therapy, Survival, and Neurological Outcome of 15 Cases With Primary Ewing Sarcoma of the Vertebral Column.

Authors:  Lida Mirzaei; Suzanne E J Kaal; Hendrik W B Schreuder; Ronald H M A Bartels
Journal:  Neurosurgery       Date:  2015-11       Impact factor: 4.654

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Journal:  Cancer       Date:  1989-10-01       Impact factor: 6.860

8.  Comparison of clinical features and outcomes in patients with extraskeletal versus skeletal localized Ewing sarcoma: A report from the Children's Oncology Group.

Authors:  Thomas Cash; Elizabeth McIlvaine; Mark D Krailo; Stephen L Lessnick; Elizabeth R Lawlor; Nadia Laack; Joel Sorger; Neyssa Marina; Holcombe E Grier; Linda Granowetter; Richard B Womer; Steven G DuBois
Journal:  Pediatr Blood Cancer       Date:  2016-06-14       Impact factor: 3.167

9.  A Comparison of Pediatric vs. Adult Patients with the Ewing Sarcoma Family of Tumors.

Authors:  Vivek Verma; Kyle A Denniston; Christopher J Lin; Chi Lin
Journal:  Front Oncol       Date:  2017-05-08       Impact factor: 6.244

10.  Adult ewing sarcoma: survival and local control outcomes in 102 patients with localized disease.

Authors:  Safia K Ahmed; Steven I Robinson; Scott H Okuno; Peter S Rose; Nadia N Issa Laack
Journal:  Sarcoma       Date:  2013-06-11
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  2 in total

1.  Primary Ewing's sarcoma of the vertebral body: A case report.

Authors:  Duo-Yi Zhao; Wei-Lin Zhang; Yan Cui; Cheng-Bin Ma; Sheng-Hui Ni; Zhi-Yu Zhang
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.817

2.  Establishing a novel prognostic tool for Ewing sarcoma patients: Surveillance, Epidemiology, and End Results database analysis.

Authors:  Feng Gao; Yuanxi Zhou; Renbo Zhao; Yingqing Ren
Journal:  Medicine (Baltimore)       Date:  2020-11-13       Impact factor: 1.817

  2 in total

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