Literature DB >> 3026112

Temperature-dependent cytocidal effects of Moloney murine sarcoma virus.

J Escobedo, B Singh, D Dina, R B Arlinghaus.   

Abstract

Infection of L6E9 rat myoblasts with Moloney murine sarcoma virus (Mo-MuSV) at 37 degrees C resulted in the killing of target cells in less than one week. However, cells infected at 37 degrees C and shifted to 40 degrees C were not killed but underwent morphological transformation and had reduced levels of virus-specific RNA. A marked decrease in a cellular 55 kDa protein, as judged by immunoblotting, correlated with increased expression of Mo-MuSV RNA in infected cells.

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Year:  1986        PMID： 3026112     DOI： 10.1016/0168-1702(86)90058-4

Source DB:  PubMed          Journal:  Virus Res        ISSN： 0168-1702            Impact factor:   3.303


  3 in total

1.  v-mos protein produced by in vitro translation has protein kinase activity.

Authors:  N K Herzog; M Nash; L S Ramagli; R B Arlinghaus
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

2.  The P55 protein affected by v-mos expression is vimentin.

Authors:  B Singh; R Goldman; L Hutton; N K Herzog; R B Arlinghaus
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

3.  v-mos proteins encoded by myeloproliferative sarcoma virus and its ts159 mutant.

Authors:  B Singh; C Stocking; R Walker; Y D Yang; W Ostertag; R B Arlinghaus
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103
  3 in total

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