| Literature DB >> 30259746 |
Byeoung-Kyu Choi1,2, Shin-Young Park3, Dong-Kug Choi3, Bora Shin4, Yern-Hyerk Shin4, Dong-Chan Oh4, Hwa-Sun Lee2, Hyi-Seung Lee2, Yeon-Ju Lee2, Jong Seok Lee2, Ji Hoon Lee2, Hee Jae Shin1,2.
Abstract
Four novel secondary metabolites possessing a unique 6/5/5 tricyclic ring system, streptoglycerides A-D (1-4), were isolated from a marine actinomycete Streptomyces sp. derived from a mangrove sample collected on Kosrae Island. Their structures and absolute configurations were elucidated by spectroscopic data and electronic circular dichroism data. Streptoglyceride C (3) showed a weak inhibitory effect on the production of nitric oxide in BV-2 microglia cells.Entities:
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Year: 2018 PMID: 30259746 DOI: 10.1021/acs.orglett.8b02411
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005