Kadir Oktay1, Ebru Guzel2, Serkan Simsek3, Aslan Guzel4,5. 1. Department of Neurosurgery, Gaziantep Medical Park Hospital, Sehitkamil District, Ertugrul Street, 27000, Gaziantep, Turkey. drkadiroktay@hotmail.com. 2. Department of Radiology, Gaziantep Medical Park Hospital, Gaziantep, Turkey. 3. Department of Neurosurgery, Lokman Hekim Hospital, Ankara, Turkey. 4. Department of Neurosurgery, Gaziantep Medical Park Hospital, Sehitkamil District, Ertugrul Street, 27000, Gaziantep, Turkey. 5. Department of Neurosurgery, Bahcesehir University School of Medicine, İstanbul, Turkey.
Abstract
INTRODUCTION: Giant cell tumors of the mobile spinal column are very rare tumors, especially in the pediatric age group. Although they are benign tumors, they have locally aggressive growth pattern and high risk of recurrence. CASE PRESENTATION: We report a 15-year-old female patient with thoracic giant cell tumor who underwent percutaneous vertebroplasty and had cement extravasation into the spinal canal. Because of the deterioration of the patient's neurological condition, total enbloc spondylectomy and cement excision were performed. She underwent instrumentation and fusion procedures in order to prevent spinal instability. CONCLUSION: The main purpose of the treatment is gross total resection of the giant cell tumor. However, adjuvant methods such as denosumab should be added to the treatment protocol in patients who are older than 2 years old and can not undergo gross total resection due to tumor size and anatomic localization.
INTRODUCTION: Giant cell tumors of the mobile spinal column are very rare tumors, especially in the pediatric age group. Although they are benign tumors, they have locally aggressive growth pattern and high risk of recurrence. CASE PRESENTATION: We report a 15-year-old female patient with thoracic giant cell tumor who underwent percutaneous vertebroplasty and had cement extravasation into the spinal canal. Because of the deterioration of the patient's neurological condition, total enbloc spondylectomy and cement excision were performed. She underwent instrumentation and fusion procedures in order to prevent spinal instability. CONCLUSION: The main purpose of the treatment is gross total resection of the giant cell tumor. However, adjuvant methods such as denosumab should be added to the treatment protocol in patients who are older than 2 years old and can not undergo gross total resection due to tumor size and anatomic localization.
Authors: Raphaële Charest-Morin; Charles G Fisher; Peter P Varga; Ziya L Gokaslan; Laurence D Rhines; Jeremy J Reynolds; Mark B Dekutoski; Nasir A Quraishi; Mark H Bilsky; Michael G Fehlings; Dean Chou; Niccole M Germscheid; Alessandro Luzzati; Stefano Boriani Journal: Spine (Phila Pa 1976) Date: 2017-09-15 Impact factor: 3.468
Authors: Tony Goldschlager; Nicolas Dea; Michael Boyd; Jeremy Reynolds; Shreyaskumar Patel; Laurence D Rhines; Ehud Mendel; Marina Pacheco; Edwin Ramos; Tobias A Mattei; Charles G Fisher Journal: J Neurosurg Spine Date: 2015-02-20
Authors: Panya Luksanapruksa; Jacob M Buchowski; Weerasak Singhatanadgige; Peter C Rose; David B Bumpass Journal: Spine J Date: 2015-10-30 Impact factor: 4.166
Authors: Maurice Balke; Laura Schremper; Carsten Gebert; Helmut Ahrens; Arne Streitbuerger; Gabriele Koehler; Jendrik Hardes; Georg Gosheger Journal: J Cancer Res Clin Oncol Date: 2008-03-06 Impact factor: 4.553
Authors: Lei Qi; Chuankun Li; Ning Wang; Haiping Lian; Minxue Lian; Baixiang He; Gang Bao Journal: Medicine (Baltimore) Date: 2018-01 Impact factor: 1.889
Authors: Benjamin D Elder; Eric W Sankey; C Rory Goodwin; Thomas A Kosztowski; Sheng-Fu L Lo; Ali Bydon; Jean-Paul Wolinsky; Ziya L Gokaslan; Timothy F Witham; Daniel M Sciubba Journal: Global Spine J Date: 2015-06-15