Literature DB >> 30258325

Implant Removal and Spacer Placement for Infected Shoulder Arthroplasty: Risk Factors for Repeat Procedures, Spacer Retention, and Mortality.

J M Cancienne1, Stephen F Brockmeier1, James C Carr1, Brian C Werner1.   

Abstract

BACKGROUND: Current studies reporting on patients following prosthesis removal and spacer placement for periprosthetic joint infection (PJI) of the shoulder have largely been descriptive and insufficiently powered to determine risk factors for outcomes other than reimplantation.
PURPOSE: The objective of the present study is to provide a national perspective on the 1-year outcomes following prosthesis removal and spacer placement and risk factors for outcomes other than reimplantation for treatment of PJI following shoulder arthroplasty.
METHODS: A national database was queried for Medicare patients who underwent prosthesis removal and spacer placement for PJI between 2005 and 2012. These patients were then evaluated for 5 major study endpoints including: (1) replantation of a shoulder prosthesis within 1 year postoperatively, (2) a repeat irrigation and debridement with second antibiotic spacer placement procedure within 1 year postoperatively, (3) in-hospital death within 1 year postoperatively, (4) a shoulder Girdlestone-type procedure within 1 year postoperatively, and (5) the remaining patients, who were considered to have a retained spacer. Patients with a study endpoint within 1 year postoperatively were included in the study: (1) mortality, (2) repeat debridement, (3) resection arthroplasty, and (4) reimplantation. While it is possible that some patients were not captured due to errors in coding, it is unlikely that patients were lost to follow-up due to change in location of services, given that the database captures all episodes of care that are coded throughout the USA. Independent risk factors were evaluated using logistic regression analysis.
RESULTS: Nine hundred seventy-five patients who underwent prosthesis removal and spacer placement were included. Within 1 year postoperatively, 21 patients died (2.2%), 70 patients had a repeat debridement procedure (7.2%), 55 patients had a resection arthroplasty procedure (5.6%), 349 patients retained their spacers (35.8%), and the remaining 480 patients had a shoulder arthroplasty reimplanted (49.2%). Numerous independent risk factors exist for all outcomes studied.
CONCLUSION: The fate of antibiotic spacers placed for PJI of the shoulder at 1 year is variable, with numerous independent risk factors for outcomes other than reimplantation. Patients with PJI following total shoulder arthroplasty should be counseled on the risk factors that influence the outcomes of staged revision for shoulder PJI.

Entities:  

Keywords:  complications; infection; revision; shoulder arthroplasty; spacer

Year:  2017        PMID: 30258325      PMCID: PMC6148586          DOI: 10.1007/s11420-017-9586-0

Source DB:  PubMed          Journal:  HSS J        ISSN: 1556-3316


  19 in total

Review 1.  Total reverse shoulder arthroplasty: European lessons and future trends.

Authors:  Ludwig Seebauer
Journal:  Am J Orthop (Belle Mead NJ)       Date:  2007-12

2.  Management of chronic shoulder infections utilizing a fixed articulating antibiotic-loaded spacer.

Authors:  Ian A Stine; Brian Lee; Charalampos G Zalavras; George Hatch; John M Itamura
Journal:  J Shoulder Elbow Surg       Date:  2010-02-04       Impact factor: 3.019

3.  Treatment of glenohumeral sepsis with a commercially produced antibiotic-impregnated cement spacer.

Authors:  Michael J Coffey; Erin E Ely; Lynn A Crosby
Journal:  J Shoulder Elbow Surg       Date:  2010-04-14       Impact factor: 3.019

4.  The Fate of Spacers in the Treatment of Periprosthetic Joint Infection.

Authors:  Miguel M Gomez; Timothy L Tan; Jorge Manrique; Gregory K Deirmengian; Javad Parvizi
Journal:  J Bone Joint Surg Am       Date:  2015-09-16       Impact factor: 5.284

5.  Prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) use for the treatment of infection after shoulder arthroplasty.

Authors:  Andrew Jawa; Lewis Shi; Travis O'Brien; Jessica Wells; Laurence Higgins; John Macy; Jon J P Warner
Journal:  J Bone Joint Surg Am       Date:  2011-11-02       Impact factor: 5.284

6.  One-stage exchange shoulder arthroplasty for peri-prosthetic infection.

Authors:  A Ince; K Seemann; L Frommelt; A Katzer; J F Loehr
Journal:  J Bone Joint Surg Br       Date:  2005-06

7.  Management of infected shoulder replacement.

Authors:  Jörg Jerosch; Markus Schneppenheim
Journal:  Arch Orthop Trauma Surg       Date:  2003-04-26       Impact factor: 3.067

8.  What treatment for periprosthetic shoulder infection? Results from a multicentre retrospective series.

Authors:  Carlo Luca Romanò; Olivier Borens; Lorenzo Monti; Enzo Meani; Jose Stuyck
Journal:  Int Orthop       Date:  2012-02-14       Impact factor: 3.075

9.  Intraoperative Corticosteroid Injection at the Time of Knee Arthroscopy Is Associated With Increased Postoperative Infection Rates in a Large Medicare Population.

Authors:  Jourdan M Cancienne; F Winston Gwathmey; Brian C Werner
Journal:  Arthroscopy       Date:  2015-11-06       Impact factor: 4.772

Review 10.  Does exchange arthroplasty of an infected shoulder prosthesis provide better eradication rate and better functional outcome, compared to a permanent spacer or resection arthroplasty? a systematic review.

Authors:  D A George; A Volpin; S Scarponi; F S Haddad; C L Romanò
Journal:  BMC Musculoskelet Disord       Date:  2016-02-01       Impact factor: 2.362

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  1 in total

1.  Benign prostatic hyperplasia is associated with increased 90-day medical complications but not peri-prosthetic joint infections following reverse shoulder arthroplasty.

Authors:  Adam M Gordon; Keith B Diamond; Asad M Ashraf; Matthew L Magruder; Ramin Sadeghpour; Jack Choueka
Journal:  Eur J Orthop Surg Traumatol       Date:  2022-08-11
  1 in total

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