Literature DB >> 3025783

A potent excitatory input to the nucleus locus coeruleus from the ventrolateral medulla.

M Ennis, G Aston-Jones.   

Abstract

Our recent anatomic experiments reveal major innervation of the nucleus locus coeruleus (LC) from the nucleus paragigantocellularis (PGi), located in the rostral ventrolateral medulla. In the present studies, low intensity, single pulse electrical stimulation of the PGi synaptically activated most LC neurons examined (69%), while a smaller percentage of LC cells (20%) exhibited pure inhibitory responses. Pharmacologic experiments suggest that the excitatory response may be mediated by an amino acid transmitter.

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Year:  1986        PMID： 3025783     DOI： 10.1016/0304-3940(86)90637-3

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  24 in total

1.  Convergence and interaction of neck and macular vestibular inputs on locus coeruleus and subcoeruleus neurons.

Authors:  D Manzoni; O Pompeiano; C D Barnes; G Stampacchia; P d'Ascanio
Journal:  Pflugers Arch       Date:  1989-04       Impact factor: 3.657

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3.  Synaptic potentials in rat locus coeruleus neurones.

Authors:  E Cherubini; R A North; J T Williams
Journal:  J Physiol       Date:  1988-12       Impact factor: 5.182

Review 4.  Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patients.

Authors:  Bankole A Johnson; Nassima Ait-Daoud
Journal:  Curr Pharm Des       Date:  2010       Impact factor: 3.116

5.  The stimulatory effect of clonidine through imidazoline receptors on locus coeruleus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotonin.

Authors:  J A Ruiz-Ortega; L Ugedo; J Pineda; J A García-Sevilla
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-08       Impact factor: 3.000

6.  Inhibitory influence of frontal cortex on locus coeruleus neurons.

Authors:  S J Sara; A Hervé-Minvielle
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

7.  Locus coeruleus bursts induced by glutamate trigger delayed perforant path spike amplitude potentiation in the dentate gyrus.

Authors:  C W Harley; S J Sara
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

8.  Citalopram and 8-OH-DPAT attenuate nicotine-induced excitation of central noradrenaline neurons.

Authors:  G Engberg
Journal:  J Neural Transm Gen Sect       Date:  1992

9.  Glutamate signaling proteins and tyrosine hydroxylase in the locus coeruleus of alcoholics.

Authors:  Beata Karolewicz; Laurel Johnson; Katalin Szebeni; Craig A Stockmeier; Gregory A Ordway
Journal:  J Psychiatr Res       Date:  2007-05-03       Impact factor: 4.791

10.  Effects of alpha 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats.

Authors:  G Engberg; E Eriksson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-05       Impact factor: 3.000
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