Literature DB >> 30257301

Meckel's Cave Meningiomas: New Classification System Focalized on Dumbbell Lesions Deriving from the Morphometric Analysis of the Posterior Petrous Apicectomy on Fresh Non-Formalin-Fixed Specimens. A Correlative Anatomoclinical Study.

Lorenzo Pescatori1, Maria Pia Tropeano2, Pasqualino Ciappetta3.   

Abstract

BACKGROUND: The Meckel's cave (MC) is commonly affected by neoplastic lesions that often require neurosurgical treatment. We simulated the posterior petrous apicectomy (PPA) on fresh cadavers to verify the in vivo feasibility of the approach. We proposed a new classification system of MC meningioma based on the extent of middle cranial fossa (MCF) involvement.
METHODS: Ten fresh, non-formalin-fixed specimens were used in this study. Through a retrosigmoid approach, 20 PPAs were performed. Subsequently, the cerebral hemispheres were removed to quantify the MCF exposure and dimensions of the suprameatal tubercle. Twenty-four patients operated on for MC meningioma were classified as follows: group 1, tumor <3 cm; group 2, tumor >3 cm. Group 2 was subdivided into to 5 subtypes: 2A, tumor of the MCF; 2B, tumor of the posterior cranial fossa; 2C, tumor of MCF and posterior cranial fossa; 2C type I, MCF <15 mm; and 2C type II, MCF >15 mm.
RESULTS: The extent of MCF exposure through the PPA is 13 mm. Mean suprameatal tubercle dimensions were 10.4 mm × 3.8 mm. Mean extent of bony removal for the PPA was 10.2 mm. PPA was successfully performed in 3 patients without major neurologic sequelae.
CONCLUSIONS: Preliminary results obtained with the PPA in 2C type I meningiomas are encouraging. The new classification system proposed can be useful in clinical practice, especially in the choice of the most suitable surgical approach for dumbbell meningiomas.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Meckel's cave; Meningioma; Middle cranial fossa; Posterior cranial fossa; Posterior petrous apicectomy; Skull base; Surgical technique

Mesh:

Year:  2018        PMID: 30257301     DOI: 10.1016/j.wneu.2018.06.222

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  1 in total

1.  Unraveling a cephalalgic quagmire from a cavern to a cave.

Authors:  S Thenmozhi; S Girija; K N Viswanathan; K V Karthikeyan
Journal:  J Postgrad Med       Date:  2021 Apr-Jun       Impact factor: 1.476

  1 in total

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