Sana Omezine1, Sofiene Bouali2, Marouen Taallah2, Alia Zehani3, Jalel Kallel2, Hafedh Jemel2. 1. Departments of Neurosurgery, National Institute of Neurology Tunis, Tunisia Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia. Electronic address: s.omezine@yahoo.fr. 2. Departments of Neurosurgery, National Institute of Neurology Tunis, Tunisia Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia. 3. Department of Histopathology, la Rabta, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
Abstract
BACKGROUND: Primary intracranial chondrosarcoma is an extremely rare malignant tumor of the central nervous system, which accounts for <0.16% of all primary intracranial tumors. This rare tumor has a high associated morbidity from the tumor itself as well as from treatment modalities. CASE DESCRIPTION: A 33-year-old man presented with a diffuse headache of 3 months' duration. He was admitted to our department with weakness in the right extremities that had persisted for more than a month. Findings of the neurologic examination revealed right hemiparesis. Cranial magnetic resonance imaging demonstrated a well-demarcated, parasagittal left frontal mass, which compressed to the lateral ventricle. It was hypointense on T1-weighted and hyperintense on T2-weighted images without creating edema in the surrounding tissue. A left frontoparietal craniotomy with complete excision of the mass was performed. The postoperative period was uneventful, and patient was discharged on the fourth postoperative day without any neurologic deficit. Histopathology showed a morphology that was in favor of chondrosarcoma grade 1. CONCLUSIONS: Dural chondrosarcoma is a possible entity in the differential diagnosis of a presumed meningioma, particularly when atypical features are present. We report a grade 1 intracranial chondrosarcoma of the classical subtype without any neurologic problems after complete surgical excision. The patient did not receive any adjuvant therapy and at 26 months' follow-up showed no recurrence.
BACKGROUND: Primary intracranial chondrosarcoma is an extremely rare malignant tumor of the central nervous system, which accounts for <0.16% of all primary intracranial tumors. This rare tumor has a high associated morbidity from the tumor itself as well as from treatment modalities. CASE DESCRIPTION: A 33-year-old man presented with a diffuse headache of 3 months' duration. He was admitted to our department with weakness in the right extremities that had persisted for more than a month. Findings of the neurologic examination revealed right hemiparesis. Cranial magnetic resonance imaging demonstrated a well-demarcated, parasagittal left frontal mass, which compressed to the lateral ventricle. It was hypointense on T1-weighted and hyperintense on T2-weighted images without creating edema in the surrounding tissue. A left frontoparietal craniotomy with complete excision of the mass was performed. The postoperative period was uneventful, and patient was discharged on the fourth postoperative day without any neurologic deficit. Histopathology showed a morphology that was in favor of chondrosarcoma grade 1. CONCLUSIONS:Dural chondrosarcoma is a possible entity in the differential diagnosis of a presumed meningioma, particularly when atypical features are present. We report a grade 1 intracranial chondrosarcoma of the classical subtype without any neurologic problems after complete surgical excision. The patient did not receive any adjuvant therapy and at 26 months' follow-up showed no recurrence.
Authors: Remi A Kessler; Mia Saade; Emily K Chapman; Rui Feng; Thomas P Naidich; Mary E Fowkes; Joshua B Bederson; Peter F Morgenstern Journal: Surg Neurol Int Date: 2021-04-08
Authors: Pedro Gonçalo Abreu; Lia Pappamikail; Carlos Pontinha; José Drago; José Artur Lourenço; Clara Romero; Pedro Teles; Joaquim Pedro Correia Journal: Surg Neurol Int Date: 2021-08-24