Literature DB >> 30256418

Indirect activation of rhesus macaque (Macaca mulatta) NK cells in oral and mucosal draining lymph nodes.

Daniel R Ram1, Kyle Kroll1, R Keith Reeves1,2.   

Abstract

The oral mucosae and draining lymph nodes are primary entry points for invading pathogens, particularly during immunosuppressive HIV/SIV infections. Innate immunity against oral stimuli, including natural killer (NK) cells, is understudied. Herein, we demonstrate functional NK cell responses to pathogen-associated molecular patterns (PAMPs) of potential oral pathogens in rhesus macaques.
© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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Year:  2018        PMID： 30256418      PMCID： PMC6161495          DOI： 10.1111/jmp.12371

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


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