Eun-Jung Shim1, Sun Hee Lee2, Nam Joong Kim3, Eu Suk Kim4, Ji Hwan Bang5, Bo Kyung Sohn6,7, Hye Youn Park8, Kyung-Lak Son9, Heesung Hwang10, Kwang-Min Lee11, Bong-Jin Hahm12,13. 1. Department of Psychology, Pusan National University, Busan, South Korea. 2. Department of Internal Medicine, Pusan National University School of Medicine, Busan, South Korea. 3. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea. 4. Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea. 5. Division of Infectious Diseases, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, South Korea. 6. Department of Psychiatry, Sanggye Paik Hospital, Seoul, South Korea. 7. Department of Psychiatry, Inje University College of Medicine, Busan, South Korea. 8. Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea. 9. Department of Psychiatry, Dongguk University Ilsan Hospital, Goyang, South Korea. 10. Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, South Korea. 11. Public Health and Medical Service, Seoul National University Hospital, Seoul, South Korea. 12. Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, South Korea. hahmbj@gmail.com. 13. Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea. hahmbj@gmail.com.
Abstract
PURPOSE: The high disease burden associated with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is linked to the elevated suicide risk in this population. Informed by the interpersonal theory of suicide, this study examined how and under which conditions depression is related to suicide risk in people living with HIV/AIDS. METHODS: A total of 202 outpatients with HIV/AIDS participated in a cross-sectional and multi-center survey involving four university hospitals in South Korea. This self-reported survey included the Hospital Anxiety and Depression Scale, Interpersonal Needs Questionnaire, and Mini-International Neuropsychiatric Interview suicidality module. RESULTS: Participants' mean age was 48.6 (SD = 13.4) and the majority was male (89.1%). The proportions of those at high, medium, and low suicide risk were 18.5%, 20%, and 15.4%, respectively. Depression was associated with suicide risk directly and indirectly by increasing perceived burdensomeness (PB) and the indirect effect of depression on suicide risk mediated by PB was contingent on the level of thwarted belongingness (TB). PB was associated with suicide risk even after controlling for depression, suggesting its independent effect on suicide risk. CONCLUSIONS: PB and TB are potential mechanisms through which depression is associated with suicide risk, supporting the applicability of the interpersonal theory of suicide to understanding a complex interplay of risk factors in people with HIV/AIDS. Moreover, given the independent association of PB with suicide risk, as well as a protective effect of TB in suicide risk, monitoring and management of these factors should be included in the care of people with HIV/AIDS.
PURPOSE: The high disease burden associated with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is linked to the elevated suicide risk in this population. Informed by the interpersonal theory of suicide, this study examined how and under which conditions depression is related to suicide risk in people living with HIV/AIDS. METHODS: A total of 202 outpatients with HIV/AIDS participated in a cross-sectional and multi-center survey involving four university hospitals in South Korea. This self-reported survey included the Hospital Anxiety and Depression Scale, Interpersonal Needs Questionnaire, and Mini-International Neuropsychiatric Interview suicidality module. RESULTS:Participants' mean age was 48.6 (SD = 13.4) and the majority was male (89.1%). The proportions of those at high, medium, and low suicide risk were 18.5%, 20%, and 15.4%, respectively. Depression was associated with suicide risk directly and indirectly by increasing perceived burdensomeness (PB) and the indirect effect of depression on suicide risk mediated by PB was contingent on the level of thwarted belongingness (TB). PB was associated with suicide risk even after controlling for depression, suggesting its independent effect on suicide risk. CONCLUSIONS:PB and TB are potential mechanisms through which depression is associated with suicide risk, supporting the applicability of the interpersonal theory of suicide to understanding a complex interplay of risk factors in people with HIV/AIDS. Moreover, given the independent association of PB with suicide risk, as well as a protective effect of TB in suicide risk, monitoring and management of these factors should be included in the care of people with HIV/AIDS.
Entities:
Keywords:
Depression; Human immunodeficiency virus; Perceived burdensomeness; Suicide; Thwarted belongingness
Authors: Matt Pelton; Matt Ciarletta; Holly Wisnousky; Nicholas Lazzara; Monica Manglani; Djibril M Ba; Vernon M Chinchillli; Ping Du; Anna E Ssentongo; Paddy Ssentongo Journal: Gen Psychiatr Date: 2021-04-09