Literature DB >> 3025151

Susceptibility of HSV strains from patients with genital herpes treated with various formulations of acyclovir.

A M Al-Hasani, I G Barton, L S Al-Omer, G R Kinghorn, C W Potter.   

Abstract

Virus isolates from 55 patients with recurrent or first-episode genital herpes, treated with various formulation of acyclovir, were tested for their susceptibility to the drug. In all but one of these patients pre-treatment isolates were available for comparison with later isolates. In none of patients, even those receiving long-term prophylaxis, was the susceptibility of the post-treatment isolates significantly reduced.

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Year:  1986        PMID: 3025151     DOI: 10.1093/jac/18.supplement_b.113

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  3 in total

1.  Effects of antiviral usage on transmission dynamics of herpes simplex virus type 1 and on antiviral resistance: predictions of mathematical models.

Authors:  M Lipsitch; T H Bacon; J J Leary; R Antia; B R Levin
Journal:  Antimicrob Agents Chemother       Date:  2000-10       Impact factor: 5.191

2.  Estimation of skin target site acyclovir concentrations following controlled (trans)dermal drug delivery in topical and systemic treatment of cutaneous HSV-1 infections in hairless mice.

Authors:  G Imanidis; W Q Song; P H Lee; M H Su; E R Kern; W I Higuchi
Journal:  Pharm Res       Date:  1994-07       Impact factor: 4.200

Review 3.  Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  J J O'Brien; D M Campoli-Richards
Journal:  Drugs       Date:  1989-03       Impact factor: 9.546

  3 in total

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